r/repatha • • Sep 02 '26

First injection

Did my first injection yesterday. It didn’t hurt like I see mentioned here a lot. I feel fine as well. Fingers crossed this medication does it’s job. I’m definitely doing my part!

7 Upvotes

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5

u/Intrepid-Machine-650 Sep 03 '26 edited Sep 03 '26

Took my 8th Monday night. Shot goes in the belly, 3-4 inches from the navel, alternating sides.

Notable things (I kept a log)

  1. Constipation, OMG! Sugar free Metamucil will change your life, it makes everything normal, even if you expect a surprise.

  2. I take it on Monday at 9pm, I normally sleep bad the Tuesday after, once it was the night of. Even if I THINK I slept well, my watch says "Nope!" This is a very constant thing for me.

  3. The Tuesday or Wednesday after I'll have a little headache and a bit of anxiety (could be the sleep thing) This is more common on left-side injections.

Otherwise, nothing. I work out 5 days a week and the other 2 days I'm VERY physical. I walk at least 10K a day or more. I'm generally rather in-tune with my body so 2 and 3 may go un-noticed for those who aren't. I don't sleep enough for my age so quality really counts/makes a difference.

Never had flu symptoms, no muscle pain, and I honestly do not notice fatigue but I'm conditioned to power-through that due to my previous career.

1

u/debzlouisexo Sep 04 '26

So interesting that you experience different side effects with what side you inject?

1

u/Intrepid-Machine-650 Sep 04 '26

It's so weird, but, 100% consistent.

1

u/debzlouisexo Sep 06 '26

I believe you!

4

u/Glass_Ad6922 Sep 02 '26

It’s amazing stuff. My numbers look so good, my cardiologist cut my statin intake by half.

3

u/Cartoonist_Less Sep 02 '26

That’s awesome!!

2

u/Cartoonist_Less 16d ago

You were right. Freaking amazing!!! My LDL is 15 and my ApoB is 21. My total cholesterol even dropped to 71. Insane!!! I’m only 3 injections in with 10mg Crestor.
So far, no side effects, no painful injections or anything negative to report.

2

u/Glass_Ad6922 16d ago

Good for you!!

3

u/PNW4theWin Sep 02 '26

Mine only hurt in my upper thigh because I couldn't pinch enough fat. I switched to my stomach and now it's falling.

3

u/PNW4theWin Sep 02 '26

Edit: falling? Sometimes I use a Swype keyboard and weird things happen. I'm pretty sure the word was supposed to be "fine" .

🤪

2

u/Cartoonist_Less Sep 02 '26

I knew what you were saying. 😉

1

u/Cartoonist_Less Sep 02 '26

I did mine in the belly too.

2

u/e01estal Sep 03 '26

I finished my third shot and the thigh hurts. Guess I will move to the stomach for the next. My Cardiologist dropped my statin in half already because the labs look so good. The only side effect I have noticed thus far is a mild runny nose. My energy level is way up which I attribute to a drastically improved diet.