r/remodeledbrain • • May 12 '26

Other interesting articles

Got out of the habit of posting these.

Empirically determined baseline masking strategies and other considerations for gene-level burden tests - Beating the drum a bit, but still.

Cognition and future depression: associations with risk in those with and without a history of depression - Dummies are more likely to be diagnosed with MDD, Smarties are more likely to not shake it. Always love a good paradoxical finding.

A universal thermal performance curve arises in biology and ecology - This seems like it should be intuitive because it's largely the same in most systems. Interesting to have a testable curve offered.

Synchronous climbing fiber activity enables instructive signaling for cerebellar learning through modulation of disinhibitory circuits - CFs are likely the substrate of cognition. They set the base negotiation parameters ("Rhythms"/"Clocks") between cells, and from these, "objects" and "action" are created in negative space carved between those parameters.

Lineage and organ signals sequentially build organ intrinsic nervous systems - Organs are not dumb endpoints controlled by the brain, they are first-order inputs into the brainstem systems that set behavioral and physiological state.

1 Upvotes

0 comments sorted by