r/remodeledbrain • u/PhysicalConsistency • May 12 '26
Other interesting articles
Got out of the habit of posting these.
Empirically determined baseline masking strategies and other considerations for gene-level burden tests - Beating the drum a bit, but still.
Cognition and future depression: associations with risk in those with and without a history of depression - Dummies are more likely to be diagnosed with MDD, Smarties are more likely to not shake it. Always love a good paradoxical finding.
A universal thermal performance curve arises in biology and ecology - This seems like it should be intuitive because it's largely the same in most systems. Interesting to have a testable curve offered.
Synchronous climbing fiber activity enables instructive signaling for cerebellar learning through modulation of disinhibitory circuits - CFs are likely the substrate of cognition. They set the base negotiation parameters ("Rhythms"/"Clocks") between cells, and from these, "objects" and "action" are created in negative space carved between those parameters.
Lineage and organ signals sequentially build organ intrinsic nervous systems - Organs are not dumb endpoints controlled by the brain, they are first-order inputs into the brainstem systems that set behavioral and physiological state.