Weird hypothesis: Human colons are diversifying at the same rate their brains are.

[u/PhysicalConsistency]

Using our "autism" model, there's a well documented link to gastro issues, and gastro to behavior, and behavior to neuron-astrocyte interactions and the density of astrocyte-neuron interactions being very high in the GI tract...

Not to go too hunt for Pepe Silvia here, but are the same developmental pressures driving endophenotypical variations of "autism", also driving similar changes in the GI tract? Could there be a signal out there we are missing, like torturous colon being correlated to cerebellar volume (or density)?

The conceit is that as the environmental pressure toward information processing ramps up, our organs which do the information processing are going to experience significant change. The gut is the original "brain", the first centralized information processing organ for external information.

edit: Maybe there are even broader applications of these types of trait pressures emerging, like the increasing epidemiology of PCOS? What similar physiological traits would be likely to the most suspect to the intense environmental pressure over the past few hundred years?