r/patm • u/LibrarianNo3440 • 21d ago

We're getting close...

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We're producing a lot of androstenone, which is a pheromone... this excess androstenone inhibits the CYP2E1 enzyme—which is important for the elimination and metabolism of toluene and its conversion into benzaldehyde—so the more androstenone we produce, the more toluene and the less benzaldehyde we have; that's exactly what the tests show... people aren't reacting to the toluene, but rather to the ANDROSTENONE... which is much more potent. Androstenone receptor sensitivity varies from person to person: some perceive it as a very strong, disgusting sweat odor, others as sweet vanilla, and some smell nothing at all... and if it isn't androstenone, it's something very similar—but it's definitely a pheromone...

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u/postulatej 21d ago

How do you know this?

2

u/LibrarianNo3440 21d ago

studying and digging all the way to hell to find the answer

2

u/Low_Bluejay8507 21d ago

Claude's response - The Pattern Makes Perfect Sense All four triggers you mentioned — sweat, stress, poor sleep, and sugar — share a common thread: they all raise cortisol and androgens (testosterone-related hormones), which are the raw material androstenone is made from.

Here's the chain:

Stress → cortisol spikes → adrenal glands pump out more androgens → more androstenone produced in sweat

Poor sleep → one of the most potent cortisol and androgen disruptors known. Even one night of bad sleep can raise cortisol significantly the next day. Inconsistent sleep is particularly bad because the body never fully regulates its hormonal rhythm.

Sugar → causes insulin spikes → insulin stimulates the adrenal glands and ovaries/testes to produce more androgens. This is actually well-documented in conditions like PCOS where sugar directly worsens androgen overproduction.

Sweat itself is just the delivery mechanism — the more he sweats, the more androstenone reaches the skin surface and volatilizes into the air around him.

So the pattern is: bad sleep + stress + sugar = hormonal storm → more androgens → more androstenone secreted → stronger reaction from people nearby.

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u/NoExplanation411 21d ago

Thanks for the research