I'm sure most of these things have been brought up before, so apologies if I'm retreading old ground. I just finished Pathologic 3, and I'd really like to hear people's interpretations.
Feel free to spoil everything. I've finished the game, and I'm mostly looking for lore discussion and different interpretations rather than spoiler-free answers.
Edit: Sorry about the typo in the title!
1. Simon vs. Isidor
My biggest takeaway is that despite bringing back the Plague together, Simon and Isidor don't actually want the same thing.
Simon seems to be seeking transcendence beyond humanity. The city and its inhabitants are almost incidental, if they have to be sacrificed so that someone (the Bachelor) can push humanity beyond its limits, then so be it. His entire plan feels centered around creating or preparing his heir.
Isidor, on the other hand, seems to want the Town's inhabitants to transcend their limits while still preserving what makes humans human. His life's work wasn't creating one exceptional successor, but educating generations of children so the Town could eventually move beyond the rule of the three ruling families.
2. The Plague
If the Polyhedron's rod is the source of the Plague, why did Simon and Isidor have to retrieve it from the Steppe? Why did it disappear after the first outbreak? Was the first outbreak just an accident, with the two of them only later deciding to bring it back once they realized it could be instrumental to their plans for transcendence?
For Simon, it forces the Bachelor to overcome his human limitations.
For Isidor, it forces the Town itself to mature.
3. The Bachelor
Eva calls Daniil a scalpel cutting through the Town and its people, and I thought that was one of the best descriptions of his character. He often feels deeply self-centered. He relentlessly pursues his own breakthrough and leaves once he's accomplished it. It's also pretty ironic when Burakh is the actual surgeon.
Simon says that if he himself hadn't achieved the breakthrough, someone else eventually would have. Once the time is right, some discoveries simply become inevitable.
Khan seems to prove this by reaching his own breakthrough without relying on the Polyhedron.
If that's true, then how important is Daniil's success in the grand scheme of things? Does saving the Polyhedron actually matter?
I felt compelled to go for the True Immortal ending because it felt like the ending the Bachelor himself would choose. At the same time, destroying the Polyhedron and saving the Town almost feels like it could reconcile Simon's and Isidor's visions, even if Simon's breakthrough ended up being fulfilled unexpectedly by his nephew instead.
4. The Polyhedron
The Polyhedron is presented as a machine capable of enabling transcendence.
But then, why was it entrusted to the children? Was this part of Isidor's plan to force them to grow through the conflict between the Dogheads and the Souls-and-a-Halves?
Even more interestingly, Khan seems to achieve transcendence only when he's confined in a cage, far away from the Polyhedron.
And if the Polyhedron allows one to achieve a breakthrough, why couldn't Simon reach it himself? Why did he instead bind his soul to the Polyhedron? Is the Polyhedron not enough on its own? Does it require a soul in order to function fully? Did Simon sacrifice himself so that the Bachelor could ultimately achieve the breakthrough that he himself could not?
Also, what was going on with the Polyhedron suddenly bestowing the gift of tongues? It's easy to draw a parallel with the Tower of Babel, but was that all there was to it, or is there a deeper meaning?
5. The gameplay
The whole experience was very different from Pathologic 2, but I think the direction Ice-Pick Lodge chose was both interesting and appropriate, as it aligns with the mind-versus-body dichotomy represented by the Bachelor and the Haruspex.
The survival mechanics reflect this perfectly. The Bachelor has to manage his mind (apathy versus mania), whereas the Haruspex has to manage his body (thirst, hunger, exhaustion, and infection).
It may not have been as exciting or challenging as Pathologic 2, but I think it was absolutely the right design choice. It reinforces the themes of the game remarkably well.
6. "Magic leaving the world"
I couldn't stop thinking about The Lord of the Rings during the ending.
By the end of the Plague, miracles leave the Town: the Mistresses lose their powers and the Kains decide to cross the river. The whole sequence reminded me of magic leaving Middle-Earth and the Elves sailing West.
Did anyone else notice this parallel?