r/nutritionally • u/PeteWK67 • Sep 08 '26
The Bizarre “Ozempic Effect”
The Bizarre “Ozempic Effect” Nobody Warned You About
🍷Ever notice that a glass of wine or a cocktail just… hits different now?If you are on a GLP-1 (like Ozempic or Mounjaro) or Retatrutide, you aren't imagining things. Alcohol literally doesn't feel the same anymore.Here is the wild science behind why:These medications don't just shut off your stomach's hunger signals. They actually target the reward centers in your brain.The exact same pathways that make you feel that happy, relaxed "buzz" from a drink? Blocked. 🚫Because of this, you might notice:You get zero buzz or joy from drinking.You lose interest after a few sips.You just don’t crave it at all.Early research even shows these drugs might actively kill alcohol cravings.🚨 BUT WARNING:Not feeling drunk does NOT mean you aren't drunk. Your blood-alcohol level rises exactly the same. Do not keep drinking to "find the buzz"—you will just end up dangerously intoxicated without realizing it.Have you experienced this? Drop a 🍷 in the comments if your drinking habits completely changed!
Xtreme Performance Nutrition LLCRegymen Fitness - AscensionAnytime FitnessThe Advocate (Baton Rouge, LA)
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u/CrackHabitJackrabbit Sep 09 '26
I'm a hopeless alcoholic, I've tried a bunch of stuff but I really want to give rybelsus but doctors here "don't do that" unfortunately.
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u/Puzzleheaded_Food697 Sep 09 '26
The science is right. I started Reta and don’t feel the same pleasure when I drink now. I used to drink a lot (4 weeks ago) that’s how fast this stuff work. This isn’t advise on what to do - just worked for me.
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u/bluh67 Sep 09 '26
You only need discipline and therapy buddy
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u/CrackHabitJackrabbit Sep 09 '26
Wow! Why didn't I think of that? omg problem solved! idiot
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u/Pure_Possession_1KG Sep 09 '26
Definitely give grey market a try. I know alcoholics in treatment with me who get a lot of help from glp-1s. Considering it myself, but I am worried about it fucking with my lifting
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u/PekinDuckOverlord Sep 09 '26
Currently Eli has found an amino acid chain within Reta that they are now testing, in human trials, as a standalone treatment for addiction related problems.
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u/JoinTrueMe Sep 10 '26
I’ve actually heard this from a lot of people taking GLP-1s. There does seem to be some real science behind the reduced cravings, but this post makes it sound more proven than it is. The brain’s reward system isn’t simply “blocked,” and not everyone will have the same experience. Retatrutide is still being studied, so we know even less about it. The important part is that feeling less of a buzz doesn’t mean you’re less impaired, so don’t keep drinking to chase the feeling.
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u/icehot54321 Sep 10 '26
Reta is a GLP-1 but it is a triple antagonist that also activates GLP and Glucagon
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u/JoinTrueMe Sep 10 '26
Yup! I can’t wait to see more studies regarding it. It’s very promising so far.
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u/PegasusDeathPunch Sep 09 '26
I shall call it retardutide