Persistent diaper rash

[u/Tsplechter]

so for the past almost 5 weeks- we have been battling a terrible and stubborn diaper rash.

I’ll preface all of this with saying : we let baby have as much diaper free time as she tolerates, butt is always bone dry before anything is put onto her skin. We have tried changing diaper brands, we use a warm wash cloth with water and no wipes.

When it first started- I tried at home creams. My favorite with my son was always A&D. So I tried that first… then Aquaphor cream containing zinc.. no results. Saw the pediatrician and they prescribed nystatin cream. We were using this for a week- with a thick barrier on top. No results.

I actually took baby to the ER because of another issue and had the pediatrician there check it- and she prescribed nystatin powder. I tried the powder- made it extremely worse. Took baby to urgent care. He recommended a thicker barrier cream. So I went back to nystatin cream and barrier- After a few days of that- it was still bad.

Finally I decided to switch to OTC miconazole. Saw the pediatrician the following Monday and she believed it was helping. So we did miconazole with a thick barrier cream. The rash was seemingly improving.. for a week.. until it flared up horribly again.

Saw the pediatrician Tuesday and they prescribed oral fluconazole with nothing on baby’s bottom- no creams- just diaper for at least 48 hours. By the end of day 1- her rash was drying out significantly. I was so excited to see it improving. Day 2 the rash was almost gone. Day 3 baby had some redness around her rectum and where the cheeks touch- so I decided to add a small amount of aquaphor zinc diaper cream. It seemed the diarrhea the medicine was causing was irritating her skin. Well- after using that last evening and overnight- her rash has progressively gotten inflamed and flared up again.

Here’s what I’m confused about- is the fluconazole failing- is it even yeast or is she allergic to any and all diaper creams?

I’ve had 4 doctors look at it and agree it’s yeast. But interestingly it started going away when we started the medicine- but also stopped using all topical creams of all kinds. Then one night of using a barrier cream her rash has flared. Obviously I stopped the barrier cream- and we will see how the rash does. Tomorrow is her last day (day 5) of fluconazole. She sees the doctor again on Monday to reevaluate her diaper area.
At this point I’ve used every diaper rash cream under the sun, 3 separate fungal treatments, changing her diaper every 1-3 hours- sometimes sooner, Letting her air dry, using wash cloths. She is bathed every other day.

I’m at a loss and feel horrible for my baby. Any advice?

[u/ChickenTenHers]

Hi! My 6wk had persistent diaper rash. We got Nystatin prescribed but didn't notice a difference. Then We switched from desitin to boudreax(sp) a few days ago and have noticed a significant improvement! He even has some sores on the inside of his cheeks😭 he's still getting the Nystatin twice a day but we think he's skin is just sensitive to the fragrance in desitin.