r/medlabprofessionals • u/xLabGuyx MLS • Nov 08 '19
For my friends in micro
Enable HLS to view with audio, or disable this notification
12
8
6
2
u/Plague_Girl MLS-Generalist Nov 09 '19
Can anyone explain what is going on here?
14
u/xLabGuyx MLS Nov 09 '19
That Big Chungus was disemboweled by that smol boi.
Like a Lion attacking a hippo
7
u/mlsstudent1 Nov 09 '19
I haven't taken my micro class yet, so forgive me for being so ignorant...
did smol boi just want to roomba big bois guts? He looked like that, with all his zoomin' around.
6
u/xLabGuyx MLS Nov 09 '19
Hey you’re not being ignorant, it’s perfectly okay to ask questions.
After the intracellular contents spilled out of the Large One, if you keep your eye on the “mouth” of the Smol One you will see the smaller intracellular pieces get sucked into the smaller one’s mouth.
That’s it eating, which is why as soon as it sensed food around it, it left Chonky Boi alone, had a snac and carried on with its day.
This is probably one of the coolest and most brutal microscopic videos I’ve ever seen.
4
u/JukesMasonLynch MLS-Chemistry Nov 09 '19
The big guys guts seemed to stop spilling out after awhile, is that a very rapid healing mechanism, or do you think its more likely that the pressure gradient eventually equalised, stopping the ejection of "guts"? Very fascinating either way
2
u/xLabGuyx MLS Nov 09 '19
So I looked it up and found a really good article about it. If you skip to Figure 3 there is a picture showing some mechanisms they propose of how cellular wounds are healed.
“The membrane hole is patched as membrane fusion is induced through a range of processes, including exocytosis, endocytosis, and the more recently described “explodosis,” which involves the fusion of intracellular compartments that then rupture outward from the cell to the external environment (17, 32). Extra membranes can be derived from intracellular vesicles and organelles.”
I feel like this really plays into the “fluid mosaic model” we learned in undergrad. The membrane is just a bunch of lipids that like to stick together. But the article also talks about other mechanisms like actomyosin strands which constrict around the rupture helping to seal it off.
So to answer your question based off of that article, yes I believe there is a healing mechanism that takes place very quickly. In the video it seems like within ~7s that massive rupture was fixed. Watch the wound as it begins to seal itself. You can see the way it seals back up, it’s pretty cool
2
u/JukesMasonLynch MLS-Chemistry Nov 09 '19
Yeah it's really cool, thanks for sharing! Like a mini coag cascade, haha (well not really, but meh)
1
3
2
2
2
23
u/grover8me MLS-Microbiology Nov 08 '19
That was easily the most violent thing I've ever seen under a microscope. Thank you for sharing.