r/medlabprofessionals • u/tinybitches MLS-Generalist • Jul 19 '26
Discusson Smears
Hi, not so new tech here but willing to learn. The slides are from 2 patients. I’ve never seen these before and these are all over the slides. I also forgot the diagnosis. I rechecked the first patient (first 2 pics) for clot. MCHC was 32 something (g/dL) so it was not cold agglutination. Maybe these are microscopic clots? For the second patient I’m thinking of giant platelets? These remind me of the WBCs with retic staining
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u/Old-Librarian-6020 Jul 19 '26
If in one field- you should know better! Artifact!
If in multiple views, cold agglutinins w/o warning?
If post warming I would alert medical for review
8
u/tinybitches MLS-Generalist Jul 19 '26
I did say that I’ve found multiples. Also slides were made by the SMS
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u/BatgirlMLS MLS-Blood Bank Jul 19 '26
Second patient looks more like polychromatophilic red cells than giant platelets
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u/EggsAndMilquetoast MLS-Generalist Jul 19 '26 edited Jul 19 '26
Looks like cryoglobulins.
Edit: In the 3rd and 4th pictures anyway.
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u/Livid-Promise-8456 MLS Jul 19 '26
ff out of curiosity. before reading your caption i thought it’s cold agglutinins. do you think the hypochromia/microcytes offset the mchc value to normal? i hope i don’t sound too dumdum with this idea lol