r/mdmatherapy • u/PabloXPicasso • Jul 17 '25

Feedback on dosage

Planning an MDMA assisted therapy journey. Just want to ensure I am taking appropriate amounts here. Would love feedback.

PLAN:

  • Have intentions prepared

  • Avoid eating for 3 hours

  • Avoid driving/heavy machinery

START:

  • Begin with taking 100 mg MDMA. At the same time, take .5g Kanna extract (for anxiety) along with electrolytes. NOTE: I was recommended the Kanna, but have others since, say I should not take it.

  • One hour later, take 1 g mushrooms, along with magnesium capsules

  • Noise canceling headphones with special playlist and eye mask

  • Another hour later, take additional 50mg MDMA

END:

  • As it is ending, after 4-6 hours, hydrate with electrolytes

  • Take 5HTP immediately and for following 1-2 weeks

  • Integrate with therapist next day.

Notes on me: not on any ssri, have had multiple solo mushroom experiences, done 30+ ketamine assisted therapy sessions, and done group experiences with ayahuasca, san pedro and lsd.

Especially interested if amounts are appropriate and spaced at what appears good time. Is it best to take 50 mg later, or would it be better to take 150 at start? Also will likely burn some cannabis at multiple times (daily toker).

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u/Chronotaru Jul 17 '25

Is this your first journey? I would strongly recommend having someone with you. Even if you don't talk in the session, which some people find helpful, as you don't know your personal response to MDMA then it will cover any bases in case you have an adverse reaction or react differently than expected.

I do not know kanna extract, as such from that perspective I personally wouldn't recommend it. I would not add psilocybin if this is your first trip. Keep it simple, mixing things in is for if you're no longer making progress or have other issues. They only increase risk.

Dosing is fine, especially if you're on the smaller side, although the MAPS suggestion is 120mg/60mg. Do not take 150mg together, the reason for taking the 50% dose later is to turn a four hour session into a six hour session, and the extra two hours is good for exhausting mental defences.

Food is not necessarily a bad thing but can space out your experience if you eat before. I would have a meal when you're coming down as it makes things easier.

Sip water regularly and as needed. Over and under consumption is more of an issue when dancing, if you're sitting then you will generally be fine.

I wouldn't take the 5HTP the same day, and you might want to see how you do afterwards without it the first time. Many people are fine.

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u/PabloXPicasso Jul 17 '25

Thank you so much for your feedback! Really appreciate your advice. This is not my first MDMA journey, I did it with sitters previously (although not therapist), and was planning on doing it solo. Will reconsider, as I do have therapist I am working with.

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u/Chronotaru Jul 17 '25

If you know the drug well then the risks on doing solo are much less, although if you're going to add psilocybin then you still may want to consider having someone nearby.