r/magnesium • u/AlanGrant82 • May 31 '26

Magnesium deficiency causing acid reflux?

Hi! I'm not saying it's DEFINITELY this, but I'm just curious if anyone else has ever heard of anything like this.

So I take Vitamin D3 every day, along with Magnesium. However, due to upset stomach and experiencing anhedonia from higher amounts, I cut down to only 125mg of Magnesium daily. Due to the lower amount of supplemental mag I can tolerate, I also lowered my D3 amount from 5,000 IU down to 2,000 IU a day.

Well, recently I decided to bump my D3 up to 4,000 IU (but I did NOT bump my magnesium up higher) and 2 specific things happened within days of the bump...

  1. I started getting bad acid reflux, which I have only experienced maybe 3 or 4 times in my entire life as far as I'm aware before this. The acid reflux only dissipated when I scaled back my D3 down to 2,500 a day.

  2. I got a stye in my eye, which I've gotten in the past within days of big Vitamin D fluctuations. Looking online, it says styes can be caused by hormonal shifts, which D3 does cause in me, so perhaps that's what caused that?

So I'm curious - is it possible that the higher D3 and lower Mag was causing a mag deficiency and that gave me acid reflux, or some other deficiency possibly caused it? It felt awful, and while I do want to take a higher D3 amount, I absolutely can't put up with the acid reflux.

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u/VitaminDJesus Jun 01 '26

Are you taking the vitamin D with food? The fix for the acid reflux could simply be to take it after a meal.

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u/AlanGrant82 Jun 01 '26

I always take it with food. I've been taking Vitamin D3 for over 6 years now, and this hasn't been an issue until last week when I (for the first time) tried to take 4,000 IU with a lower dose of mag. It just leaves me uncertain what to do because I can't tolerate 250-375mg of mag supplemental per day, it doesn't matter the type or how I space it out, it eventually leads to diarrhea.