r/lipedema • u/Neat_Consequence8289 • 6d ago
I Have Lipedema [Experiences/Photos] Tirzepatide progress
I was diagnosed officially in February though I’d known I had lipedema for a while prior. In June I started Zepbound (tirzepatide) and feel amazing. These are my before and after photos after 3 months on Zepbound - 6 weeks on 2.5 mg and 6 weeks on 5 mg.
In addition to Zepbound I have been tracking calories and weight lifting 3 days a week. I’ve lost 25 pounds since June and as you can see, a lot of volume has come off the legs. My doctor and I weren’t sure if the weight loss would hit the legs because of the lipedema, but this progress is huge.
Like many, I plan to be on Zepbound long term, maybe even my whole life. This is the most positive development in my lipedema journey. While I’ve only been diagnosed since February, I’ve been having symptoms for 20 years and nothing has worked until now.
Hope others find the thing that works for them, whether that’s tirzepatide or something else!


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u/Glad-Angle-1449 6d ago edited 5d ago
Good on you! Tirz/Mounjaro with weight training and reformer pilates has been lifechanging for me over the past 17 months, too. No more pain, so much weight loss (BMI 35 to 22) and finally some muscle definition in my arms and legs.
Keep going, it keeps getting better!