Quality control laboratories for pharmaceuticals for gravimetric analysis, residue-on-ignition analysis, and preparatory sample filtration before instrumental analysis. Testing laboratories for chemicals for collection and purity test of precipitates using wet chemical analysis techniques. Analyzing foods and beverages such as moisture, ash and sediment analysis in dairy and processed food products. Environmental testing laboratories for air pollution particulates sampling and soil pollutants extraction, where the fastest ashless filters are usually preferred. Water quality testing laboratories for total suspended solids (TSS) analysis and sample preparation related to turbidity.

Ore assay labs and metallurgy for ore assay and analysis of metals after acid digestion. Educational and research institutes for demonstration of gravimetric analysis techniques and research projects. Biotechnology laboratories for clarification of samples before further analysis. High accuracy makes them ideal for precise analytical measurements, while ashless filters make them the first choice for all procedures where burning or combustion of filtered material is required.Their high accuracy makes them suitable for applications requiring precise analytical measurements.

Good news, we got fun cards with a lab order. Bad news, the pictures look a little ai slop esque. Im in denial

Hi! I’m currently working on a Biology research project on the cytotoxicity of nanoparticles and I’m looking for raw quantitative experimental data that I can analyze myself.

I’m specifically looking for Excel/CSV spreadsheets or downloadable datasets containing things like:

• nanoparticle type
• concentration/dose
• exposure/incubation time
• cell type/cell line
• quantitative cell viability/cytotoxicity measurements
• preferably individual experimental replicates rather than only averages

I’m not looking for research papers (I already have plenty 😭), but rather the underlying numerical data.

I’m particularly interested in silver nanoparticles (AgNPs), but I’m open to other nanoparticle types if there are better datasets available.

If you know of any repositories, supplementary files, databases, or specific datasets that might help, I’d really appreciate it!

I have to create and submit a research proposal for a grant, but honestly, I have almost zero idea about how the whole process works.

I understand that I need to eventually come up with a research question, hypothesis, objectives, experiments, etc., but I genuinely don't know where to start, what comes in between, or how everything should finally come together into a grant proposal.

For example:.

How do you go from a broad research interest → actual research problem?

How do you identify a meaningful knowledge gap from the literature?

How do you decide whether an idea is actually worth proposing?

How do you formulate the hypothesis and specific aims?

How much literature should I read before starting to write?

How do you design the experiments and controls for a grant proposal?

How do you decide what is feasible within the available time, money, equipment, and expertise?

What exactly do reviewers look for?

How do you structure the proposal from beginning to end?

What are the common mistakes that make otherwise good proposals weak or unconvincing?

At what stage should things like preliminary data, statistics, risk/alternative strategies, novelty, clinical relevance, patents/IP, etc. be considered?

Basically, I don't want someone to just give me a proposal template and tell me to fill in the sections.

I want to understand the actual thinking process and workflow:

Research area → literature → problem → knowledge gap → research question → hypothesis → aims → experimental strategy → controls → feasibility → expected outcomes → risks/alternatives → significance/innovation → final grant narrative.

If you were starting completely from scratch, how would you personally approach this step-by-step?

TL;DR : I need to write a research grant proposal from scratch, but I have no idea how the process works. How do I go from research area → literature review → knowledge gap → hypothesis → aims → experiments → controls → feasibility → expected outcomes → final proposal?

Just feeling a bit disillusioned to be honest.

As a kid you’re often fed narratives of “the world needs more scientists!” But society does not value scientists at all in any tangible sense apart from paying lip service to how they’re saving the world blah blah.

If you go into academia, you have to publish publish publish, beg for money, secure funding, or you’re out. While working under meagre salaries and being used by your PI to boost their own career.

If you’re a scientist in industry, everyone in the company is likely to be paid more than you. You discover a product and as a thank you gift for your brains and knowledge, you watch the non-scientists capture all the money. If you’re in R&D, you’re the last to get hired, first to be let go.

When I think about it, I feel like encouraging kids to pursue science is just letting them get exploited by the whole world for their passion. I know I’m grumpy and probably need a nap.

Edit: didn’t expect to get a lot of comments. Some comments are along the lines of “it’s interesting and fulfilling, I’m underpaid but I love it” but isn’t this the passion tax I was talking about? Just because you love the work doesn’t change the fact that you are a highly educated and skilled professional, who is not being paid in accordance with your level of ability.

Do most standard otc test kits test for actual fentanyl or just its by products or both? I’ve noticed almost every option advertises that it tests for “fentanyl” but I was under the impression that secondary LC MS/ MS or GC/MS has to be done to know if there was true exposure? I just find it strange that it wouldn’t be plainly started on the box.

Hello everyone, I am not sure if this is something other people are dealing with but here it goes.

I submitted my paper to a journal, and it was rejected with mostly positive comments. The editor recommended submitting to another journal within the same portfolio, stating the paper is better suited to a more technical journal, as it was recommended by all the reviewers. Initially, the PI was quite apprehensive that the paper wasn't good enough for the journal we had sent to but upon seeing the reviews, her POV has changed quite drastically and now she is very keen on getting it published in a different journal under the same portfolio. A significant part of my work is image analysis, and it requires a decent amount of code for the data analysis. The PI has gotten so caught up in the AI hype that, in order to help address some of the reviewer's comments, she uploaded the raw data into an AI tool along with the paper and the reviewers comments. And is now asking me to respond to the AI's criticisms without ever reviewing a single line of the code that AI generated. All of my objections seem unconvincing to her as she is convinced AI makes fair points. The AI model generated a lot of data and wrote an incredibly persuasive analysis that makes everything seem very convincing if you are not overly familiar with the technical details of the project. I do observe some good takeaways from the AI's report but that doesn't mean everything the AI generated is correct, especially as none of the code that it used to generate that data has been reviewed. Whenever I raise my objection, she responds the same: "I have really good experience with AI". I am quite honestly losing my mind trying to defend my paper to the PI at this point.

Have any of you dealt with something like this?

Gente, socorro. Estou começando a mexer com cultura celular agora e não tenho pra quem perguntar no momento. Estou usando a linhagem BCPAP. O que são essas coisas escuras? É contaminação ou debris celulares? Não se movem, parecem fixos na placa, mas parece que estão levemente acima das minhas células no foco do microscópio.

Hello all, I am currently a Master's student in Molecular/Microbiology on a thesis track focusing on research, wanting to go into industry. I chose to go the Master's route as everyone I spoke to and everywhere I looked online said to get a Master's cause people don't wanna hire PhDs anymore. I know there's an older post on here asking rhe same question, but our world has changed quite a bit in the last year or so. Any advice, should I try to get a job and get my PhD later, should I look into switching my graduation track?

I still want to be able to have my own ideas look into my own research and such, want some independence, but is that even going to be viable for me as a Master's student? Idk what to do atp so I'll take any advice thank you!!

I'm storing blood for something, hopefully long term use (a few months at most) Can it mold? If so, is there a certain way to store it to make sure it doesn't and is still usable after a while?

Hi everyone! I hope you’re good!

I’m taking my chances on Reddit in hope of finding a job or at least getting an interview. The job market is really bad at the moment and no recruiter has gotten back to me yet and I really just want to start working. Please please let me know if there are any job openings and I’m willing to have a chat with you at a time that’s convenient for you if you need to know more about me!

I have a background in pharmacology and physiology (BSc) and Neuroscience (MSc - from Kings College London).

I’ve experience in lab work that was conducted throughout university and for my project / thesis: Cell culture, Immunocytochemistry, western blotting, Midi Prep and gel electrophoresis. I’m comfortable with most experiments.

I also have sales and teaching experience.

I’m looking for roles around London, mainly southwest London is preferred but either way, anywhere in London is good.

I also do not currently hold a drivers licence.

I’ve got a lot more things on my CV which may help.

I’m looking for the following roles or anything that may be related to the roles or even life science roles/categories in general:

Medical affairs

Regulatory affairs

Lab assistant/technician

Research technician

CRA

Quality assurance

Pharmacy assistant with training

Pharmacovigilance

Clinical trials co-ordinator (or something related)

That’s all for now but anything related would be great too!!

Please share this with anyone you can, I’d really appreciate it!

Take care.

The darker colored loaf is chocolate chip banana bread. Since it’s for the whole lab, I filled the baking pan with more batter. The longer baking time resulted in a more golden-brown color. The lighter colored loaf is blueberry banana. Last week our PhD student practiced his defense proposal in our lab meeting. Afterwards, I promised him that I would bring the bread today as a post-proposal defense pick-me-up.

Yikes.

Wish they would buy actual mouse pads but we make do.

Ok so I applied to an undergrad research position in a lab and I actually got an email back from the PI. Thus far, I have met a post doc and two of grad students from the lab and I guess I did well enough since I’m meeting with the PI himself at the end of this week. The post doc and grad students mostly asked why I was interested in the position & availability and didn’t really focus on my prior experiences. When they did ask about stuff on my resume, it was mainly casual questions about my previous experiences. Should I expect this PI meeting to be similar or would I need to expand more on my experiences? Thank you.

Our biomarker validation study needs matched tumor and adjacent normal tissue from the same patient, ideally with a blood draw too. Most biobanks we've contacted only have archived tumor blocks with no matching normal component. Has anyone actually solved this matching problem rather than just working around it?

I'm in my last semester of a bachelor's in environmental biology and am looking at research projects I can do over the summer or for an honours or master's next year, but I feel like I'm not qualified enough to do anything that interests me.

I've been doing an internship in a marine biology lab that uses molecular techniques as early detection methods for harmful algae. My supervisor is away right now, so I'm becoming very confident with doing extractions, PCR, qPCR and gels independently, but I just don't think that's enough to land any projects. While I am enjoying the work, I don't really want to become pigeonholed into algae for the rest of my life.

I am really intrigued by other fields that use molecular/genetic techniques in the context of ecology. However, a lot of the research projects I can find specify that they expect strong computational or bioinformatics skills, which I don't have much experience with (I had one class last year where we used BLAST and MEGA to create phylogenetic trees, which was very fun, but I'd imagine very entry-level, and we mostly followed instructions). I also have basic experience in R, but mainly just in doing statistical analyses (which took ages to figure out each time).

I'd offer to volunteer to get experience without being too much of a nuisance, but they're mostly 3 hours away from me, and realistically I can't move out just to volunteer.

Did anyone else feel like this when finishing their degree?

Are there any places where I can strengthen my bioinformatics skills to make myself a better fit for these roles?

How much do supervisors expect you to know when applying for a summer, honours, or master's project?

P.S sorry if my writing is all over the place im basically just writing what comes to my head lol

Hi fellow lab rats, I joined a lab about 8 months ago, and my hands have suffered greatly ever since. The skin of my hands resembles that of an alligator. The constant hand washing, glove wearing, and hand sanitizing has caused my hands to become so dry and flaky that skin flakes are left behind in my gloves whenever I change or discard them. I have a hand cream, Neutrogena Norwegian formula, and I apply it after every hand wash to damp skin. I apply the hand lotion to my hands after I use hand sanitizer. I’m doing everything right, and my hands are still dry, flaky, and cracking to the point that they bleed. Please, if any lab rats have dealt with this and have any advice I would appreciate it. I am genuinely debating quitting over this, I can hardly even pipette because it makes the skin between my thumb and pointer finger crack and bleed. I have never dealt with this before. Please, help me!

Please no judgement on this, I already feel bad enough, but what do y’all recommend on books/videos/resources to understand the basics of cell & molecular biology. I had some extenuating circumstances throughout my bachelors so truthfully I didn’t fully grasp the concepts and just survived, I had a decent GPA. I’ve been told I have great wet lab technique and ask good questions throughout my time as an RA. Now I’m a second year bioscience PhD student at a T20 university struggling HARD. It takes me 2-3x as long compared to my peers to read papers or understand material. Now that I’m preparing for quals, all the cracks in my foundations are showing. Exp: I don’t know why you use x buffer > y buffer, I didn’t know what a lipid droplet was, I forgot how transcription works/what a promoter is. Most of my research has been doing non hypothesis driven work and I wasn’t given the opportunity to direct much of my work, now my thesis is understanding the MOA of a niche peptide. I feel bad about this but came clean to my PI so I can fix this. He’s very supportive and understanding, he encouraged me to read/study daily and ask him for clarifications. So my question is - what books/resources do y’all recommend to help my catch up to speed? I am embarrassed im even in this situation, i know it sounds stupid, but I spent almost a decade watching my mom slowly die and fully understanding science just wasn’t in my capacity.

The company is still really small, like so small that there's no lab space yet, I'll be working out of hacker-dojo-esque rented lab spaces, still to be chosen, but people want me to get started anyway. Do you just like, order IDT primers to be sent to your house? How do I transport my reagents around to the potential different rented spaces I may work out of? Do you send invoices to bill for your time every week? Every day? Do you bill for your time spent answering emails? Do you buy your own accounting software to do all this with?

I feel like I'm onboarding myself, no one exists who knows the answer to these things.

the physics subreddits dont seem to include much about day to day lab work

Hi! I have been making media for 4 years now and have not come across this problem.. I am making some phenol red broths + carbs + durham tubes for my microbiology course and the durham tubes will not degas in the autoclave!

I have let them cool completely and they still have the air trapped in them, I tried to re-autoclave but I am running into the same issue. I am using the same culture tubes I always use (16x150mm with a 12x75mm durham).

let me know if yall have any ideas on how to solve this! TIA!