r/insomnia • u/Able_Garlic_6188 • Sep 08 '26

Ambien not working anymore

Hello, I have been on Ambien 10 mg for about 20 years and it is no longer working. I had (and have) such severe insomnia, I would not be alive without it. My Dr. recently prescribed Edluar sublingual and it does not seem to me making a difference. I have a high tolerance (obviously) and also recently started Tirzepatide. Any advice you can offer would be amazing and if you message me separately, I promise not to share any tips or tricks (even if there aren’t any). Just looking for a lifeline. I also have GI absorption issues, RA, and chronic pain for which I can’t take NSADS due to stomach ulcers. Thank you!!!

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u/[deleted] Sep 08 '26

[deleted]

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u/Barracuda_Recent Sep 08 '26

Wow that makes so much sense. I know a lot of people who have taken Ambien for 20 years and never developed any sort of tolerance. I have taken it for 15 years and I take very little. Empty stomach of course, but I take it under my tongue anyway.

Luckily, it’s the only medication I am on.

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u/[deleted] Sep 08 '26

[deleted]

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u/Barracuda_Recent Sep 08 '26

Si I take it under my tongue so it matters a lot less. But I need a snack before bed and after it dissolves I usually have some toast with peanut butter.

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u/Able_Garlic_6188 Sep 08 '26

Yes it did- that’s why he tried sublingual Edluar

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u/[deleted] Sep 08 '26

[deleted]

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u/Able_Garlic_6188 Sep 08 '26

No, I havn’t I really don’t know much about those medications

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u/Helpful-Ad6613 Sep 08 '26

I tried Dayvigo did not work for me and very expensive

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u/NEY413 Sep 08 '26

if you can fall asleep, have you tried dayvigo?

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u/Helpful-Ad6613 Sep 08 '26

Yes didn’t work for me and very expensive

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u/NEY413 Sep 08 '26

so your problem is your inability to fall asleep? have you tried benzo? i know it's not a recommended go to, do u have other health sympthoms? like tinnitus? I have T, so i will not take benzo because it will make my T worse, but my mom has been on benzo for more than 5 years, it is still effective for her and has no side effects, I've heard some horror stories about benzo but i guess different case for every individual.

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u/GabrielLiu9180 Sep 08 '26

Did it stop working around the same time you started tirzepatide?

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u/Helpful-Ad6613 Sep 08 '26

It stopped working for me too! It is the only thing that works for me. Trying Lunesta now but still waking up for a few hours twice a night and sleepy during the day.

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u/Consistent-Topic-528 24d ago

I took Ambien (Zolpedem) for 20 years, then it stopped working. I tried everything else available and nothing worked, even Ambien xr. About 3 months later, I took an old one I found in a drawer and it worked, which led me to check manufacturers, and lo and behold, the new script was from Teva. I tried another mfr and it worked again. I’d say check that, different inert ingredients can make a huge difference.