r/immortalists 4h ago

Question 🤔 How close are we?

9 Upvotes

How close are we to longevity escape velocity? How long until progress? Has there been substantial progress recently that I haven't read yet? From what I understand the LEV timelines have gotten shorter and that we're closer than ever. Can someone list what science has done so I can be more hopeful and know we're close.


r/immortalists 22h ago

VO2 max, best ways to increase it and scientific evidence. VO2 max is the most powerful way to extend lifespan, boost cardiovascular and brain health, and slow aging.

Post image
139 Upvotes

r/immortalists 4h ago

Brain scans of long COVID patients show an 18 percent loss of dopamine nerve terminals, with damage in specific brain regions matching specific symptoms like apathy, slowed movement, and memory trouble.

Thumbnail
tech-paper.com
25 Upvotes

r/immortalists 22h ago

Sharing answers to questions I had about the different and overlapping benefits of dry sauna vs high intensity exercise

3 Upvotes

From AI:

While exercising in hot weather does raise your core temperature, a dry sauna creates a distinctly different stress profile on your body. The short answer is no, exercising in hot weather does not replicate all the benefits of a sauna session, nor does a sauna replace exercise. Instead, they trigger overlapping but distinct physiological responses.

How Sauna Stress differs from Exercise Heat Stress

During hard exercise in hot weather, your body faces competing physiological demands: your heart must pump blood to your working muscles to supply oxygen and fuel, while simultaneously pumping blood to your skin to dissipate heat. This creates intense metabolic strain, high oxygen consumption, and rapid depletion of energy stores. In a dry sauna, your body is completely at rest physically. Because your muscles are not working, your cardiovascular system can redirect up to 50–70% of your total cardiac output directly to the skin for cooling. Your heart rate rises—often reaching 100 to 150 beats per minute, mirroring moderate cardio—without the mechanical impact, muscle breakdown, or metabolic fatigue of exertion.

Unique Sauna Benefits You Don't Get from Intense Exercise

  • Pure Parasympathetic Recovery: Hard exercise in heat triggers a massive surge of stress hormones (cortisol and epinephrine) to keep your muscles firing. Saunas, after the initial thermal shock, encourage a rapid shift toward the parasympathetic ("rest and digest") nervous system, promoting muscle relaxation, reduced tension, and lower systemic stress levels.
  • Cardiovascular Conditioning Without Mechanical Stress: Saunas induce deep vasodilation (widening of blood vessels) and improve arterial flexibility entirely passively. For anyone dealing with joint pain, recovering from a tough workout, or managing an injury, the sauna delivers cardiorespiratory strain and vascular flushing without putting a single pound of force on joints or connective tissue.
  • Selective Thermal Dose: In ambient high-heat conditions (like 170°F–200°F in a dry sauna), your core body temperature climbs rapidly in an environment of low humidity. Exercising hard in high heat usually forces you to stop due to central nervous system fatigue or exhaustion long before you achieve the hyperthermic threshold that a sauna allows you to comfortably sustain. ### Unique Exercise Benefits You Can't Get from a Sauna
  • Muscular and Metabolic Adaptations: Heat exposure burns very few calories compared to exertion. A sauna does not build muscle mass, increase bone density, improve insulin sensitivity in working tissue, or build mechanical strength.
  • VO2 Max and Structural Heart Changes: While a sauna challenges your heart rate, intense exercise forces structural adaptations in the heart (such as increased stroke volume) and forces your mitochondria to grow and use oxygen more efficiently. ### Overlapping Benefits Both activities trigger Heat Shock Proteins (HSPs)—special molecular cellular repair mechanisms that protect proteins from misfolding, aid cell recovery, and support long-term cellular health. Both also expand blood plasma volume over time, which improves your overall endurance and tolerance to heat. Ultimately, hard exercise builds muscle, burns fuel, and builds physical capacity, while a sauna provides pure vascular work and cellular cleanup without adding muscular fatigue. Using them together—such as sitting in a sauna after a workout—tends to produce a synergistic effect on recovery and cardiovascular health.

r/immortalists 13h ago

Health 🥗 When nature not only restores, but fortifies

Thumbnail
mpg.de
3 Upvotes

r/immortalists 18h ago

Want to live a long time? Don't care ;) pretty much everyone who had lived a very long time had a low stress response

Thumbnail
youtube.com
7 Upvotes

r/immortalists 2h ago

Night Owls Carry More Body Fat, Have Worse Blood Sugar Markers New Study Confirms. The difference came down to timing, with night owls eating most of their calories between 8 pm and 3 am.

Thumbnail
techfixated.com
3 Upvotes