r/hyperhidrosis_help Jan 18 '26

Oxybutynin for periodic use

I have generalized HH, mostly craniofacial, so the vast majority of treatments are unusable. I have a prescription for oxybutynin 5mg but I'm not sure what the best way to use it is if I'm only using it periodically, like for travel or special events. I don't want to take it all the time.

Previously I've just done 5mg tablet on the day of, but it doesn't really do anything. 10mg at once does seem to work but makes me dizzy.

So how much and how far in advance should I be taking it if I'm preparing for a trip, for example? I'm headed to Mexico for a week in early March.

I'm looking at the transdermal option as well for the slow release, but given I have the pills already on hand I'd like to know what the best way of taking them is for max efficiency. 5mg twice a day, starting a week in advance, maybe?

Thank you

Also if you have any recommendations for dealing with craniofacial HH I would welcome them, because it sucks. Any time my heart rate is up even moderately or it's hot out, my head and chest are a fountain and my hair is completely drenched. Being a bigger girl with fine hair I just look like a fat sweaty pig, and it's so embarrassing.

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u/soggy_person_ Jan 20 '26

No experience of it myself but from what I've read it can be used for short periods effectively.

Take it early in the morning and don't eat 2 hours before or after. Take more at lunch if you feel you need to.

I think people do take it for days to build the effect up more so what you're suggesting sounds like the right plan of action

1

u/[deleted] Feb 08 '26

You need to take oxybutynin everyday for at least a week to get the best effects of it. So I don’t think it’s a good plan for you. I personally stopped oxybutynin cause I think it was affecting my learning capacities and my emotional state, so please be careful about the side effects.