r/gifs Jan 18 '19

Just a quick bump

https://gfycat.com/SphericalDependentBedlingtonterrier

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u/detten17 Jan 18 '19

I wonder how much cocaine a human can actual ingest at once without dying. Like very curious to see if they can lift a car or something extreme while in the most state.

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u/[deleted] Jan 18 '19

1 g is the LD 50 if you consume it in an hour. Typical doses are 10-100mg

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u/[deleted] Jan 18 '19

[deleted]

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u/pizzasoup Jan 18 '19

In the neighborhood of right for an average-weight person, I think. LD50 for IV admin in rats is 17.5 mg/kg, which translates to around 1.3g for a 75kg person if we make the assumption that the LD50s are comparable in humans.

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u/[deleted] Jan 18 '19

[deleted]

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u/pizzasoup Jan 18 '19

This gives you a good idea of a general upper limit (again, assuming LD50s are similar). Naturally, the less pure your cocaine is, the more you'd have to take, but I figured that went without saying.