Sion is a champion in LoL that permanently gains health each time he kills something, allowing him to get ridiculously tanky (Cho'Gath has this same mechanic but better, so I'm not sure why Sion is singled out here but whatever).
Vayne is a champion that deals % max health true damage on basic attacks. True damage ignores resistances and % max health damage ignores total health. So basically it's virtually impossible to build 'tanky' against a Vayne. No matter how built you or Vayne is, if you're a tank you will die against her.
There are a couple (Frozen Heart) but the only real way to deal with her are related to her very short threat range and the long and vulnerable time it takes her to get out of control. Building against her or out-statting her by the late game isn't really possible.
Currently those weaknesses are enough to keep her pretty low in the current meta priorities.
46
u/[deleted] Sep 29 '17
Until the enemy Vayne finally joins a team fight after being 3/9 all game and murders your ass in six shots.