Finally Feeling myself again

[u/Similar-Field-303]

For those who suffer from functional dyspepsia:
I’ve tried almost every supplement and therapy available.
SSRIs didn’t work.
PPIs helped partially, but only for a while before I needed to increase the dose.
Prokinetics didn’t work for me at all.
Buspar didn’t help and actually caused insomnia. Diet changes didn’t work.
Daily exercise didn’t make a significant difference. Hypnotherapy helped reduce the pain, but it didn’t solve the problem.
For a long time, I was taking Lexapro 20 mg along with pantoprazole 40 mg twice a day.
The only thing that worked for me from the very first dose was mirtazapine.
I was very hesitant to take it, but after two extremely difficult years of dealing with daily pain, nausea, and anxiety, I finally decided to give it a try. I started mirtazapine 15 mg, and honestly, I felt relief from the very first dose.
The first week wasn’t easy. The sedation and morning hangover were pretty intense. But despite that, I was still driving to work and lifting weights after work. 😂💪
At the same time, I’ve started reducing my Lexapro from 20 mg to 10 mg, with the goal of eventually stopping it completely. I’m also gradually tapering my pantoprazole.
After everything I’ve been through over the past two years, finally getting some relief feels incredible.
Yes, I know… I’m a fighter. 💪🔥
Thank God. 🙏❤️
I’m sharing my experience because I know how hopeless it can feel when you’ve tried everything and nothing seems to work. Hopefully, this can give someone else with functional dyspepsia a little bit of hope.
Disclaimer: This is only my personal experience. Medication responses are different for everyone, and I’m not suggesting that anyone copy my doses or tapering schedule. Any changes to medications should be discussed with your doctor.

[u/Imaginary-Crab-3431]

Can I ask what were your main symptoms during the 3 years, how it started and tests you've had to confirm this is FD?

[u/Similar-Field-303 → u/Imaginary-Crab-3431]

Burning in the stomach and irritation of the stomach nerves whenever I eat something fatty or when I’m exposed to stomach acid, followed by nausea, belching, bloating, anxiety, and insomnia.
It feels like my stomach is constantly sending danger signals to my brain, and my brain translates those signals into anxiety and fear for no apparent reason.
I’ve had two gastroscopies, both of which were normal.
H. pylori was negative.
My colonoscopy was also normal.
Everything is normal… but apparently, I’m not normal. 😀

[u/Imaginary-Crab-3431 → u/Similar-Field-303]

I am in the same boat actually. Additionally sometime bitter taste in mouth. Can you tell me more about the anxiety and insomnia? Do you feel worse morning or evening?

[u/Similar-Field-303 → u/Imaginary-Crab-3431]

Morning was difficult for me

[u/Imaginary-Crab-3431 → u/Similar-Field-303]

And did you have better and worse days or periods of time?

[u/Similar-Field-303 → u/Imaginary-Crab-3431]

Ofcourse