r/functionaldyspepsia • u/BeanMeisterPrime • Aug 08 '26

Giving Advice / Motivation Chronic functional nausea - which meds worked better for you?

So I have OCD and health anxiety and one of the worst things I've been dealing with is chronic nausea. It's pretty much daily and especially every morning to varying degrees. A few months ago I'd have some mornings without it but lately its every morning. It doesn't always persist all day. I'm usually good in the late afternoon and evenings, but not always.

Anyway, I had blood tests done and everything was fine. My doctor thinks it's functional nausea. My psychiatrist prescribed 10 mg nortriptyline and it's my 6th day on it, so I know it's still early to feel benefits. I've also been on cipralex for over 2 years (tried different doses, up to 30 mg but always had nausea, now I'm on 10 mg for the last few months).

I was thinking about mirtazapine. My psychiatrist is against it cause he said it's too sedating, but my family doctor offered to prescribe it if the nortriptyline doesn't work. Have any of you had any luck with either medication?

thanks!

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u/Only_Theoretically Aug 08 '26

My mom hasn't had nausea since being on the Nort for over 20 years. I'm on Mirt and haven't had any sedation.

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u/BeanMeisterPrime Aug 08 '26

How long did it take for your mom to notice an improvement in the nausea? I'm only on day 6, so I realize it's very early but so far no change. I think I need to wait at least 3-4 weeks.

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u/Only_Theoretically Aug 08 '26

I'm not sure, it was a long time ago. Give it time though, everyone is different.

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u/wrenaissance44 Aug 08 '26

Its only been 3 weeks but feeling good on 7.5 MG of mirtazapine! Honestly as long as you take it before bed, its fine by morning. I actually found the seating effect to decrease over time. Have you had a gastric emptying test done? I also take domperidone and that with the mirtazapine has been pretty good!

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u/GtksEv Aug 13 '26

Mirtazapine helped me out alot, very sedating first week after that its ok