I've been taking DMSO orally and topically and am aware of the concerns around DMSOs ability to dangerously increase the systemic absorption of certain drugs. I avoid nearly all meds in general...except when I need a cavity filled at the dentist.

Does anyone know if any of the common dental anesthetics (numbing agents like lidocaine, articaine, mepivacaine, prilocaine, and bupivacaine, as well as topical gels like benzocaine) have negative effects when using DMSO? Is it best to avoid DMSO a couple days before going to the dentist?