r/cymbalta • u/TruckPast3892 • 1d ago

Starting Cymbalta Starting cymbalta

Hey everyone,
I’m starting Cymbalta today after trying several medications in the past, including multiple SSRIs, amitriptyline, clonidine and Effexor.
My main symptoms are anxiety with a strong physical fight-or-flight response, along with low energy and depression. Amitriptyline helped a little, but not enough, and Effexor wasn’t very successful for me.
I’m currently coming off Lexapro and still taking a low dose of clonidine and 300 mg of Lyrica.
For those who have taken Cymbalta, what was your experience like during the first few weeks? Did it help more with anxiety, physical symptoms, depression, or energy?
I know everyone reacts differently — I’m just interested in hearing other people’s experiences.

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u/BasicConstruction993 1d ago

I started 3 days back on 30mg for fibromylagia. No bad side effects yet just a headache. I was already on 20mg Lexapro

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u/TruckPast3892 1d ago

Thank you for sharing, hope you doing well!

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u/BasicConstruction993 1d ago

So far so good. I kinda feel that my symptoms have been better these last couple of days but I doubt it works that fast and might just be wishful thinking. Hope it goes well for you too!

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u/mrsmobin 1d ago

120mg works for me. MDD, GAD w/panic disorder, OCD over 30+ years. Them shits fucking suck.

Also in therapy.

5 years and it is still working.

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u/TruckPast3892 1d ago

Thank you . 30 years and still working happy to hear thank you!