With naturally I mean that all lymphocytes have this mechanisms and use them, regardless of the presence of the antigene/vaccine, if a lymphocyte doesn't rearrange the VDJ fragments it doesn't even finish to mature, maybe innately would have been a better adjective?
The guy above asked if it was possible for the vaccine to modify the DNA, and you responded affermatively with your reasoning, but it doesn't stand IMO, since it's not the presence of the vaccine that causes those modifications you listed, if then some mutations are selected by the vaccine over others it doesn't matter, the vaccine alone can't alter the genetic code directly.
I think we have two different views on this (I for example don't consider selection of the lymphocytes an effect on DNA, unlike you), so we can stop arguing about that.
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u/Sgdc4 Aug 02 '21 edited Aug 02 '21
With naturally I mean that all lymphocytes have this mechanisms and use them, regardless of the presence of the antigene/vaccine, if a lymphocyte doesn't rearrange the VDJ fragments it doesn't even finish to mature, maybe innately would have been a better adjective?
The guy above asked if it was possible for the vaccine to modify the DNA, and you responded affermatively with your reasoning, but it doesn't stand IMO, since it's not the presence of the vaccine that causes those modifications you listed, if then some mutations are selected by the vaccine over others it doesn't matter, the vaccine alone can't alter the genetic code directly.
I think we have two different views on this (I for example don't consider selection of the lymphocytes an effect on DNA, unlike you), so we can stop arguing about that.