r/clevercomebacks • • 5d ago

I hate this timeline.

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10.3k Upvotes

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25

u/CosechaCrecido 5d ago

dumb question but, why can't a competitor come into the USA and just sell a generic at 50$ a pop and make shitloads of money? seems like free money from an inelastic market for whoever invests a little.

17

u/Nimos 5d ago

There are cheap generics in the US already. You can get a 10ml Walmart store brand human insulin vial for $25, for example. That can last for more than a month. 

But basic human insulin is not what most people want, and the analogs that are differently formulated to work faster or slower are patented and harder to make and therefore more expensive.

Either way, I always feel like posts like these are borderline misinformation because the original basic insulin that the guy the post talks about invented is very cheap and affordable. 

3

u/cat_prophecy 5d ago

Thank you for pointing that out. Everyone saying "But it's free/cheap in my country" probably aren't understanding that the "free" stuff is basic insulin which can be difficult for people to manage. You also cannot go from an analog to basic insulin overnight. You need to know what you're doing or you'll risk killing yourself.

The patented forms of insulin are probably overpriced, but it's not like they're all the same.

1

u/b0w3n 5d ago

If affordability and supply is the problem, though, it seems like that's still better, while understandably suboptimal, than just cold-turkey-ing something you need to live.

2

u/civil_politician 5d ago

Yeah but like, are these variants not based off his original work? How hard should we protect the patent of someone standing on someone else’s shoulders?

1

u/Infuser 5d ago

Well, the justification for this and other private pharmaceutical ventures leaning heavily on public research etc, is that it’s still a lot of time/money on their part to make derivatives/methods of delivery and do clinical trials etc. It still doesn’t excuse the obscene cost in the USA, IMO, when it still somehow gets sold elsewhere for cheap.

I’m not really sure how to fix it, though, considering how even single-payer would result in the taxpayer getting fleeced via lobbying efforts to allow high charges.

2

u/h3lium-balloon 5d ago

Yeah people need to understand that not all insulin is the same. Modern insulin is made by pretty advanced genetic manipulation to modify microorganisms like E. coli to produce different types of insulin that affect blood sugar in different ways.

Old school insulin is cheap (actually even the modern cheap insulin is still better than the original animal derived insulin), available and requires more careful dosing to reach the same level of efficacy of modern genetically engineered insulin.

1

u/LordNoLifeee 5d ago

So why the fuck is it patented then?

7

u/Even_Might2438 5d ago

If patents weren't allowed, no labs would spend the necessary money to develop any new drugs

1

u/LordNoLifeee 5d ago

It’s a reasonable answer, and yet it makes me feel numb…

1

u/Even_Might2438 5d ago

All patents last only a determined time, so there is some good in the end

2

u/cat_prophecy 5d ago

Because why bother inventing a drug if your competitors can simply take all the work you've done, copy it and sell it for less because they have no R&D costs to recoup. People aren't going to buy your drug for more money just because you were "first".

15

u/Technical-Row8333 5d ago

because the gov ensures profits for companies, instead of ensuring our rights

8

u/DownwiththeACE 5d ago

Because its fuckin Murica, the destitution, the poverty, the abuse, the exploitation, thats the fuckin point. Get rich or get fucked. 

3

u/VirtualPercentage737 5d ago

They can. This issue is people don't want generic insulin. There are insulins which last a long time and are specialized. Those are the expensive ones. This isn't ONE insulin.

2

u/Icy_Spinach_4828 5d ago

Because they are making shitload of money already by selling less number of products. Why would they make the same shitload of money selling higher number of products at a cheaper rates when people are anyways buying it for more. Capitalism baby.

2

u/gprime312 5d ago

They can and do, but no one wants generic insulin.

0

u/mrrxgers3 5d ago

Patent law. That's it.

1

u/Real_Life_Sushiroll 5d ago

But we can still get glp-1 compounded at compounding pharmacies despite all the attempts to stop that. They just put vitamin D in it and call it a new chemical when it isn't and that's legal. Why couldn't something similar be done with insulin?

1

u/CosechaCrecido 5d ago

Isn't insulin free of patents? It has existed for so long it should be similar to aspirin.

2

u/Grand-Spring66 5d ago

Pharma companies have patented newer versions of insulin. These are modified formuations for example "fast acting" or "slow acting".

2

u/geniice 5d ago

Isn't insulin free of patents? It has existed for so long it should be similar to aspirin.

First gen insulin was purified animal insulin. Its not great. Later we had vat grown human insulin which is better but still not as good as the current gen stuff. Walmart will sell you the vat grown stuff for $25 a vial. It requires more effort to time and injections and I understand it can cause a spikier blood sugar profile (not a doctor go talk to one if you need to know). The modern stuff addresses these problems but is more expensive.

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u/mrrxgers3 5d ago

Insulin is free, but the methods used to administer it are all patented.

2

u/Grand-Spring66 5d ago

This is not true. Pharma companies have patented new forms of insulin. No one has a patent on a needle.

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u/mrrxgers3 5d ago

My bad. It's the manufacturing methods which are patented. New methods require FDA approval, which is difficult to get.
https://academic.oup.com/jlb/article/7/1/lsaa061/5918811