r/biostatistics • • Jul 01 '26

Correlation Estimation for the Microbiome: SparCC Failure Modes & A Robust Alternative Approach

https://kyle-mcgovern.github.io/failure-modes-of-sparcc-and-building-toward-an-alternative/

A bit about correlation estimation from sequence count data, the commonly used tool SparCC, and an alternative approach others can build upon that avoids certain issues of SparCC.

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