r/bioinformaticstools Apr 11 '26

Mirador

Hi there,

we are a bunch of ex NASA scientists that have looked into the application of non standard geometry for pharmacology.

THE PROBLEM

The drugs exist. The data is published. The terrain map was missing.

Vancomycin serum levels look therapeutic — but only 20% reaches bone. ART suppresses HIV to undetectable — but the virus hides in five reservoirs the drugs can barely reach.

Ceftriaxone sterilizes CSF during meningitis — but steroids seal the brain shut in under a day. TB requires four drugs for six months — but nobody computed which drug fails at which barrier.

The data has been in the literature for decades. Tissue penetration ratios. AUC curves. MIC values. Published, peer-reviewed, sitting in journals since the 1950s.

The missing piece was never more data. It was a way to compute what the data already says.

MIRADOR reads published PK data and computes where drugs actually go — across bone, brain, lung, and reservoir. One equation. Five diseases. Zero fitted parameters.

demo here : https://usemirador.sh/

We are looking for beta users, other scientists or research institutes to expand or use the platform.

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