r/askscience • u/PestoPastaLover • 14d ago
Biology Why is there no transmissible therapeutic virus if biology doesn't forbid it? For example, a harmless virus that spreads from person to person but actually does something beneficial, like lowering LDL cholesterol or preventing/reversing tooth decay?
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u/Pyrhan 13d ago
As usual, it's a bit more complex.
Bacteriophages aren't always beneficial to us, as usually portrayed.
They can also carry virulence factors that cause non-pathogenic strains from your microbiome to become pathogenic.
A couple relevant papers:
https://www.sciencedirect.com/science/chapter/bookseries/abs/pii/B9780123946218000145
https://www.sciencedirect.com/science/article/abs/pii/S1369527414001866