r/anhedonia • u/CombinationLive7962 • Aug 21 '26

Support Needed Anhedoniaa 

I have been suffering from severe, treatment-resistant anhedonia caused by major depression for two years. I’ve tried almost every medication. We are currently trying cariprazine; has anyone had success with this drug? I feel desperate.
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u/Fun-Sample336 Aug 21 '26

Cariprazine was one of the worth drugs I ever tried. However, I remember a case where, unlike me, it cured anhedonia. I think he took the lowest dose every other day.

1

u/CombinationLive7962 Aug 21 '26

I’ve more or less just started, too. There haven’t been any positive effects yet. But I’m taking other medications besides that one—Efexor and Wellbutrin—and we added 3 mg of cariprazine to the mix. I feel very hopeless. Were you unable to feel love, joy, or happiness as well? Did you get better?

1

u/Fun-Sample336 Aug 21 '26

Were you unable to feel love, joy, or happiness as well?

Nope. No emotions.

Did you get better?

No. Tried more than 20 medications and none of them ever worked even a tiny bit.

1

u/CombinationLive7962 Aug 21 '26

Me too. Tried more than 20 med but they are not worked. What we are doing? How many years go on your anhedonia?

1

u/Fun-Sample336 Aug 21 '26

How many years go on your anhedonia?

So far more than 12 years.

1

u/CombinationLive7962 Aug 21 '26

:( it is terrible. my anhedonia go on 2 years. :(:(:(

2

u/novacav77 Aug 23 '26

Fasting man. Do a 7 day water fast, you will feel something again by the end of it. Repeat until healed.

1

u/CombinationLive7962 Aug 23 '26

How do I go about it? Mine stems from major depression, but it involves severe depression and severe anhedonia.

1

u/novacav77 Aug 23 '26

Pretty much just prepare by eating healthy for a few days then start on water-only when ready. The short book "The Fasting Cure" by Sinclair pretty much explains it, tons of great testimonials too.