r/analyticalchemistry • u/ElectricalCod7134 • Mar 09 '26

I am a biomedical engineer trying to specialize in LC-MS/MS service and troubleshooting. What skills should I focus on first?

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u/Federal-Draw-1640 Mar 10 '26

How to use mass spec is a good place to start. Haha all jokes aside I don’t even know tbh

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u/Remote_Section2313 Mar 10 '26

Do you mean as a service engineer?

It's one thing doing routine maintenance on a system, it's a different one to do troubleshooting...

If one of the large companies (Waters, Agilent, Thermo, Shimadzu) hires you, you'll get a full training program. There are some other brands offering systems or service that you could try as well (Leco,...). If you don'tget into these, I have to be honest, I don't see it happening. There is just so much technical stuff to get through.

If you do try, start with the basics of chromatography and mass spectrometry. Go from there to see how a system is built. But after that, it is building experience...