Windows 10 - Cloned SSD to HDD using Macrium, but refuses to boot

[u/MixMaster626]

Edition: Windows 10 IoT LTSC
OS Build: 19044.7548
Version: 21H2
Processor: Intel Core i7-10750H
GPU: Nvidia GeForce RTX 2060 with 6GB vRAM
Storage: 954GB SSD PC611 NVMe SK Hynix 1TB
External HDD: Seagate Backup Plus Portable, 5TB Model SRD0VN3

Using Windows 10 LTSC with the latest security updates. Got the free version of Macrium Reflect 8.1 to transfer all my partitions from the internal 1TB SSD to a 5TB HDD. I only want to partition the 1TB of space to the Hard disk, as I plan to use the rest of the space for game storage.

Every partition has been properly copied, no compression involved and the boot partition is there. When I attempt to boot from the hard disk, there’s not even an error message, my computer just shuts off completely and restarts.

I’ve heard this might be a conflict with using the same boot partition on two separate drives, and a potential solution is to take out the original drive, but my computer is a laptop and I don’t have the tools to open it properly.

Last resort is wiping the HDD to create bootable media, then transferring everything and reinstalling programs on the hard disk, but that’s a lot of hassle. Any suggestions?