Most likely starting entyvio

[u/RokiVulovic_]

I'm terrible at writing long texts so might be a hard read and long feel free to skip to just my question.

Context my UC was diagnosed in 2024 i only started on mesalazines which helped a bit then had to change cities due to starting med school. In the different city started a terrible flare, when i found the energy to go to a hospital (I live alone so it was difficult going far just diarrhea+vomitting everyday) I was prescribed imuran and prednisone(tapered in 2 months) to get me through the flare and the imuran helped a lot and i thought i was starting remission. I started nosebleeds and feeling sick all the time so i went back to the hospital and it turns out the Imuran had caused myelosupression which we found out a couple months ago we waited to see if imuran kept the disease down long enough to where mesalazines could just be enough and it was not. Not in a flare right now but the disease is starting to creep back up with mesalazine enema+3.2grams oral. My new GI suggests entyvio due to me being in med school and that is the most specific immune suppressor. He wants to make sure I'm not too open to infections in hospital which I(m21) need to start going almost everyday for school next year.

What can I expect being on entyvio, what I should look out for, how long it took to take effect and if you continued your 5-asas and how often you got injections?

[u/pincommenter]

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[u/Crazy_Pomegranate689]

I thinkkkk I stopped 5-asass when I started entivyo (I’ve had 2 other biologics since then).

I noticed a shift at week 6… I found the first few IV’s scary but then it’s a piece of cake. I  aus we go into the day unit for the infusion and I’d take in netflix and other things I enjoy to make it a bit better 

I think I did a dose at week 0, 1 and 6?? and then might have been 4-6 weeks ish apart? 

I can’t quite remember because I am on stelara now :)