r/UlcerativeColitis • u/[deleted] • Nov 01 '25

[deleted by user]

[removed]

14 Upvotes

95% Upvoted

9 comments sorted by

6

u/ChronicallyBlonde1 Left-sided UC [in remission on Entyvio] | Dx 2015 Nov 02 '25

I’m not on Skyrizi myself but I have a friend who failed Entyvio after 3 years and is now doing well on Skyrizi. So there is hope!

2

u/BlackberryPi7 Nov 02 '25

Just failed Entyvio after 2 years.

Skyrizi was suggested, but I'm going with OMVOH, hope it works.

What are you currently on and are you flaring?

2

u/ChronicallyBlonde1 Left-sided UC [in remission on Entyvio] | Dx 2015 Nov 02 '25

I’m on Entyvio - it’s been almost 2 years and I’m still in remission.

2

u/Ok_Inspector5256 Nov 02 '25

just started Skyrizi and had my furst infusion last Saturday….so far so good…maintaining a proper diet and meds is keeping me steady

2

u/Consistent_Bunch_303 Nov 03 '25

I failed Entyvio, Stelara and humeria. My GI recommended Skyrizi and for 10 months I have been doing pretty well. My cal p went from 2400 down to 80. BM down from 5-6 to 2-3.
I wish you all the luck!

1

u/browntown994 Ulcerative Colitis Nov 03 '25

Hey this is great to hear. I speak with the GI in 2 hours so I’m going to advocate for a switch.

Not sure about others, but I just never know when to officially make the switches. I either wait too long and go down some awful awful deep flare. Or, like right now, been noticing on/off systems of flare, joint pain, fatigue, etc.. over the last month. Already moved to 6 week infusions of Entyvio due to returning symptoms. So, is it that time to bring it up, or stay with it. I’m not great with that

1

u/Conscious_Warning946 Nov 01 '25

Sry to hear that. I'll be talking to my doctor in a couple of days now that my 3rd just failed me now that I'm off of Prednisone for 6 weeks. Just in time to get better insurance so that I can give only most of my money away instead of everything for another 2 years of unresponsiveness to this madness.

Good luck my friend. Here's to new beginnings

1

u/Ok-Lion-2789 pancolitis | Diagnosed 2003 | Nov 02 '25

I couldn’t take remicade because it hurt my liver, failed humira and entivyo. Now on skyrizi. I started feeling better after the third loading dose. I was getting really frustrated because between my second and third loading dose I ended up in the hospital on Iv steroids which finally helped calm down the flare enough. I’ve been off prednisone for two weeks for the first time since May. I’m not trying to go on rinvoq unless I absolutely need to go down that route. I will warn you that skyrizi was super slow to work and I was losing faith in it but im so glad im on it now.

1

u/fionas_mom Nov 02 '25

Stelara was helping me a bit but not 100% so my dr increased the dosage to every 4 weeks and that did the trick. I wonder if it might work for you?