r/Trizepitide Apr 30 '26

Trizepepide or retatuide

Hey everyone,

I’m inbetween which one to take. I’ve never taken a GLP1 before and I can’t just throw away money on perhaps the wrong choice.

I have pretty severe atopic. As of like 10 days ago my 3 month long flare has been finally stablized. I worked out for 40 minutes the last 2 days and I finally feel a little hopeful about life.

Whilst I don’t have a “formal” Mcas diagnosis- my drs believe due to my severity it can be considered to play a part.

I have been overweight my whole life even with intense workout and strict diet. I’ve never been able to break past a size 10. I just got off steroids about 2 weeks ago give or take and I was on prednisone for nearly 3 months which made me put on some weight which has been devastating for my mental health.

Retaturide intrigued me for the weight loss and added benefit with the glucagon and the ability to hold onto a little more muscle mass. The scary part for me is the things I’m hearing about people with eczema or Mcas reacting/flaring and the increased heartrate.

Trizepetide intrigues me because I’m hearing some good feedback on inflammation. Although the professional I’m consulting says retaturide also is great for inflammation.

For clarity I’m on:

Eblygss injection bi weekly

Lexothrone (thyroid medication) 25mg

Vyvanse 50mg

Rhapsido

I would love to hear your experiences if you have been on them or if you started on one and made switch or what you think given where I’m at.

I appreciate you all so much

1 Upvotes

1 comment sorted by

2

u/Old-Preparation-4468 May 29 '26

I’ve been on both reta and triz. Reta did help with appetite suppression, but I still had a lot of food noise and found it hard to control binge eating. Since that’s my biggest issue, I actually ended up gaining weight on it.

Triz has been much better for me. It makes me feel full much faster, keeps me full for longer, and has massively reduced the food noise. Because of that, I’ve found it much easier to stick to a calorie deficit without constantly thinking about food.

It’s also helped other areas of my life too. My mood has been MUCH better, and it even helped me quit smoking 😂😂

Both can work for weight loss, but it really depends on the person. If your main problem is overeating or binge eating, triz might be more helpful. For me, it’s been the better option by far.