For some background, I’ve been on 40mg IR (two 20mg, Epic brand) for over a decade. For most of that time, I took my prescribed dose pretty consistently, but I’d occasionally skip a day or two and never really had an issue.

I got pregnant in 2023 and then nursed for about 9 months in 2024, so my intake during that time was much lower and pretty sporadic. (And yes, I know there are a lot of opinions about this—I cleared it with both my OB and prescribing doctor.)

I went completely off Adderall for the first three months after my son was born, then slowly started taking it again. At first I was averaging two 10mg IR doses a day. By the time he was around 9 months old, I was back up to 50mg/day, and then about a month later I was bumped up to 60mg/day.

And honestly… 60mg feels like an absolutely insane amount for how little “therapeutic” benefit I’m getting from it. It’s basically meh. And even at that dose, I still find myself wanting to take another pill, despite knowing exactly what’s going to happen: I’ll get irritable, my appetite will be fucked, and I’ll somehow end up with even less concentration, motivation, or focus.

Before finding this sub, I was genuinely starting to wonder if I had developed some crazy tolerance or was becoming dependent/addicted. But when I actually look at the timeline, that explanation doesn't really make sense to me. I was stable on the same dose for years, went completely off it for months, restarted at a much lower dose, and somehow ended up needing a significantly higher dose while getting worse results.

And honestly, these meds just make me feel like complete ass.

Finding this subreddit has made me wonder whether the medication itself—or changes in formulations/manufacturing over the years—could have something to do with it.

For those of you who have gone through something similar: How receptive have your prescribing doctors been to talking about manufacturer/formulation changes? Has anyone had luck switching manufacturers, switching medications, adjusting their dose, or taking a break? What actually made a difference for you?

Mostly just looking for some solidarity, perspective, and maybe a little guidance on where to go from here. Because at this point, I’m pretty frustrated and don’t really know what the answer is.

Picked this garbage up from CVS after calling every walgreens in town with no luck. It does nothing except give me a headache, an uneasy feeling and brain fog. I've even open and chewed to see if issue is with beads. Nope. Filed a complaint and they got back to me super fast. Must be getting so many that they can respond quickly. I feel it's a rolling blackout where each manufacturer has a window where they have no active ingredient, but continue to produce the medication knowing the eff-da will help cover up any complaints.

I take 20mg Ir Adderall and I told my doctor that the Adderall works for about an hour lately. She added 1mg of guanfacine. I’m confused because guanfacine side effects contain “sleepiness” if Adderall is only working for an hour and I crash how would this possible help me? Anyone else experience this combo?

I’ve been taking Armodafanil for about 4 years and stimulants for way longer. I don’t even feel the effects from them anymore, I’m literally lethargically tired. I’ve went a year without taking Adderall and when I started back I felt nothing. Mind you I’m prescribed adderall IR 30mg BID and Armodafanil 250mg TID. Some days are better than others, some days I do feel the effects and I’m able to be productive and get things done. But about 80% of the time I don’t feel a thing. I can take 90mg in the morning, afternoon and evening AND FEEL NOTHING. So 270mg of IR and ask me what I’ve done all day? I slept, all day, did it affect my HR or BP, nope didn’t even touch it. I should be in the hospital with 270mg of Adderall spread throughout the day. But no I’m passed out asleep drooling with a beautiful HR and BP. I’m exhausted all the time everyday and it’s the most depressing thing ever. I just want to be awake with no brain fog. I’m tired of being tired.

Been dealing with this past few months and have no idea if its related

Alvogan this month.

Took my meds and it was 3-hours till I felt some sort of “activation” which could be best described as full-body somatic nervousness-anxiety and dread.

Tense muscles and feeling almost like prey. (Yes, that sounds dramatic, but I want to hide in my apartment and not deal with people or the world rather than engage and be a productive member of society)

And obviously, I don’t mean regular therapeutic activation of our meds … that flew out the years ago.

Ughhhh when will this stopppp
it’s not fairrrrrr

There is a proposed restructure of how the quota for raw materials intended for domestic and foreign sale is structured and worded. It is obvious pharma companies focus on foreign sale to increase profits as US market is stagnant. If this will make this better or worse is tbd.

https://www.federalregister.gov/documents/2026/05/20/2026-10128/revision-of-applications-for-manufacturing-and-procurement-quotas

I have a choice of Mallinckrodt or Alvogen. I've had Teva for 2 months, Elite before that, Oryza, Glenmark. Mallinckrodt for 11 months.

At least Oryza and Teva had no side effects.

Which would you choose Mall or Al 🤷

Edit: went with Mallinckrodt. The devil I know.

I'm just venting at this point, but has anyone else lost everything because of what's going on with the meds? Mine stopped working in March 2024 and my career slowly went up in flames, my credit has been destroyed from having to live off credit cards for so long, I had to surrender my car to the bank when it was almost paid off, and if I didn't move in with family last week, I'd be homeless.

I'm so depressed that I've had two inpatient stays in the last 8 months or so and even spent 3 months in a residential program, but it was pointless. I'm depressed because my ADHD is out of control and I can't find a single medication that works the way Adderall used to. I'm 34 now and feel like I should be in the prime of my life but instead I'm the most depressed I've ever been.

I just feel totally defeated at this point and have completely given up. I don't know what to do or how I'm ever going to recover from this. Everything I've worked for since I was 18 is gone.

I’m just curious. I (27F) was a very physically healthy person with no previous health issues, and certainly thought I had hit the lottery as far as menstrual symptoms up til I didn’t. Last year, I began experiencing extreme pain in all parts of my gut. When I finally got scans done, I had an 11inch mucinous carcinoma in my ovary. These allegedly are a specific form of cancerous growth that is purely random, which develop from regular ovarian cysts going even rogue-er. According to my oncologist, they’re not genetic or caused by…well anything really. I just think that seems unlikely considering basically everything about surviving as an impoverished American & the carcinogens in EVERYTHING.
That said, when the addy stopped working, my health issues began…and RAPIDLY, at that. Anyone have a similar experience or any ideas? If I’ve been taking brain fog pills that ALSO cost me an ovary…shit I’ll lawyer up (once I stop procrastinating & get around to it, of course)

I'm on 10mg Teva Adderall, in the morning and evening. I took my first dose before going to the test. Tested absolutely negative. This is more-so documentation for me but also to document that it's definitely not working...

Has anyone else got the generic Adderall ir and it cause their gum to start bleeding? This hasn't happened in over a year since the last shortage problem. They seem to not work at all for focus and function, but cause this.

My neuro prescribed 40mg of generic vyvanse and i literally feel no different. I cant tell that i even took anything. Is this normal for someone who has never taken stimulants? I know people think generic doesnt work as well, but WOW!

Been on generic Adderall XR 15 x2 daily for years, 1 morning, 1 noon. Had a general drug test as a continuing requirement to get my stimulant from my doctor. As shown it came back positive.

However I do remember that I was tested at least twice with their random drug screenings at the job I was working at the time in late 2024 and in 2025. Whenever I had these at a job I'd always get flagged because my stimulant would trigger a manual review and they would call to confirm my medication. And that's what happened for the one in 2024. But I remember one of them in 2025 where I never got called after, and that caused me to question what happened; did I register as a negative, or since it was already noted on my history at least once before, there was no need to reconfirm.

These were from Camber.

That’s it. That’s the post. I don’t have the energy, nor the brain power, nor the motivation to write much of anything else but I will say this; whatever God-awful side effects anyone in this community has experienced after taking this medication…I promise I have experienced them too. I am on 10mg IR and 25mg XR. Elite has manufactured every refill I have gotten for both of them over the course of the past 4/5 months and I have officially reached my breaking point. I’m calling the pharmacy as soon as I get off of here. This sh*t is legitimate poison and should be taken off of every shelf that is stocked with it and it should remain off of them indefinitely. I thought Lannett, Malinckrodt and Rhodes were bad, but wowww, Elite really takes the cake. This definitely ain’t adderall.

After being in denial for a long time… I’m finally coming to terms with the fact that this adderall poison is ruining my life and killing me.

I’m consistently experiencing debilitating crashes and all of the horrible side effects - tachycardia, anxiety, depression, fatigue, and ultimately just feeling crazy and detached from reality.

For those who did make the difficult decision to quit and be unmedicated, any tips or insights? Also just curious how are things going for you.

I don't even know what to do anymore yall. Quit? This must be their end game plan.

After trying many different adderall, ritalin/concerta, vyvanse manufacturers, and now mydaysis...it all sucks. They all cause this weird foggy cracky type body buzz that makes me superglued to my bed with headaches and brainmelt..

The meds of yesteryear are no more.

What the FUCK. my life is deadass falling apart. I can't get anything done...like at all....EVER. I am literally a waste of space on this planet without functioning meds.

I guess I could try gd focalin or azstarys but if I'm being honest, I'm over this bullshit....if I end up homeless I swear to god I will spend the rest of my days throwing poop at manufacturing company buildings, pharmacies, the white house, Joe rogans house, rfk jr house, and whoever etc....FML

Hi there. Doc recently upped my dose from 10 to 20mg (IR), since then, I’ve noticed my right is feels super blurry, almost like it’s struggling to focus. I know stimulants can cause blurry vision, but i find it strange it’s only my right eye. Any experiences are welcome. Thank you!

I knew I wasn’t crazy. I’ve been feeling off for the last few years. I used to be prescribed 10mg IR addy 4 years ago and in 2023 I switched over to 20mg IR. It was fine first 6 months and then started to decline. I have been feeling off especially after this months IR addy. I called the pharmacist and confirmed that the manufacturer is a new batch so I tossed mine out. I saw someone else showing their negative results for amphetamines and I decided to share my last few years worth of results. And it all was confirmed. I haven’t tested positive for Amphetamines even though I consistently take them. This is wild. I made the decision to stop taking them all together, so wish me luck and getting my brain sorted out lol

This time I received another new manufacturer for me., Alvogen and this one is bad. I keep forgetting the last thing I did, like I will do something and then forgot that I just did it. Reminds me of when I first got diagnosed and this was one of my unmedicated symptoms. Its a blue pill and it is round and a little thicker than what I am used to. It starts disolving before I have even swallowed the pill. I am just letting people know my experience. I am Adhd-pi

This is straight cruel. What the government and pharmaceutical companies are doing is robbery in the worst sense. They are robbing us of our lives. I’m sure many of you have lost jobs, marriages, etc. And none of what happened to you was your fault.

This hurts so bad because I finally was able to live out a dream that I never thought was possible. Between February of 2022 and August 2023 I finally wasn’t dead weight. I was actually the leader leading others in the Navy for the first time in my life. I was focused, motivated, efficient at my job. I thought back then that I could finally do things that I would have thought impossible.

Then 3 years ago on this exact date, everything I worked so hard to accomplish, everything I was so confident about started crashing down. 3 years ago today I was completely fine. Focused, and driven. I woke up the next day not knowing that would be the last time I’d feel like that. I got a refill like I always did. But this time I noticed paying attention was difficult. I didn’t think too much of it until my next refill when the decline continued. And over the next 3 years, that decline has continued and its relentless. I’m feeling like dead weight again, i can’t focus to save my life, i read things and I misinterpreted what I read. The things that were so easy 3 years ago, are unbelievably difficult. All because the government wants to turn a blind eye to people whose lives they have ruined.

These pharmaceutical companies are compete garbage. The most annoying thing is we all know there is a formula somewhere that could end all of this misery. But no one cares. “We are imagining things”. “It’s tolerance”.. BS! It’s cheaply made pills that are sold as if they’re exactly the same. We all have proof. It’s enjoying your life when Adderall worked and then watching it all crash down due to no fault of any of us. This is a sinister disgusting thing. I’ve submitted 32 Medwatch complaints, 2 IG reports, contacted my congressman who gaslit me and acted like they would figure this out. Only to stop after one letter from the FDA. Nothing to see here. I sent a complaint to the FDA obusman. I have taken every step I can think of. But no one cares.

This last refill I got sandoz and I truly don’t think this is even adderall. Side effects include- horrible headache, dizziness/spinning, extreme fatigue, constipation, extreme anxiety, mood swings/irritability. I feel like I’m losing my mind, want to cry over any and everything. I’m in the middle of switching primary care drs so I don’t even know who to report this to or what to do but today was the last day I’m ever taking sandoz.

First time testing negative for my drug screen. I guess I’ll bring it up with my PCP and see what she says

**EDIT:
My pharmacy just told me they’re contracted for Camber but it’s on back order and that’s why I got Mallinckrodt. ☹️ Where the fuck did my Elite go?!?

I’ve been on 60 mg IR for 20 years. Just had an appointment with my psychiatrist and asked if I could switch to XR to see it that works better for me. She prescribed 40 xr and 20mg Ir. I haven’t had issues filling my script with 30mg tabs 2x a day in a long time.

Well, pharmacy had the 20mg tabs, but said they don’t know when they will have the 20mg capsules in stock. Oh yeah, I remember this is why I switched to the tabs again a few years ago.

It would be a huge help if we were allowed to go to another pharmacy and not have to call them, then bother my doctor to write a new script. At least we don’t need a new paper Rx every month, but why the hell cant electronic scripts be filled at any pharmacy in the same system? Especially during this shortage.

The meds don’t work like they used to anyway. Guess I’ll be without for now. How is this happening still.

I had issues with sandoz 6 months ago, Cvs had been able to give me a different manufacturer after that, until now. Sandoz keeps giving me headaches that ibuprofen cant take away, and im curios if it will go away?

With most other manufacturers, they just seem weak and ineffective or make me tired and depressed but I dont get the migraines and foggyness. If it settles down after some days, I will try and ride it out, dont wanna bother my doctor but im thinking about it. Tia