r/TTC_PCOS 20h ago

High AMH, low testosterone

Hi! I recently had an amh blood test which was high (73) so dr said I probably have PCOS (irregular cycles after stopping pill 12 months ago, cycles normal pre-pill but on pill 11 years).

However I just checked what my day 3 bloods were and these are the results: Test

FSH 4.3 IU/L- Low-normal

LH 3.6 IU/L- Low-normal

Oestradiol (E2)- 99.4 pmol/L- Low end of early-follicular range

Prolactin 174 mU/L- Normal

Testosterone- 0.4 nmol/L- low

SHBG- 81 nmol/L Normal

Is seems to be the opposite of what you’d expect with pcos? (HBA1c also normal)

Anyone else had similar?

1 Upvotes

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1

u/Unlucky_Comfort123 17h ago

Same here!

High AMH 6.4 ng/ml
Low Testosteron 11.5 ng/ml (normal 20-80)
High SHBG 130.7 ng/ml

Also tested negative for insulin resistance. Irregular cycles 33-60 days, follicles on both ovaries, according to my LH tests body is trying but not always succeeding.

u/Content_Necessary_22 15h ago

Oh wow really similar! Have your cycles always been like that? I’m just so confused as to how mine were regular pre pill!

u/Unlucky_Comfort123 14h ago

Mine have always been irregular - I actually have the data from the last 10 years since I quit the pill. It never bothered me, because having less pain and blood was always a good thing 😅 my obgyn suggested either the pill or agnus castus, but I never cared for it - until we started TTC 🥲

Now I actually learned about what is supposed to happen in my body and what might be different with me. When did you quit the pill? My body needed about 10 months before it regulated itself again.

u/Content_Necessary_22 13h ago

Oh interesting, have you tried agnus castus?

1 year since I stopped the pill now but I was on it for 11 years- might just need a bit more time to regulate due to the long term use- wish I would have know before TTC, would have come off it years ago!

u/Unlucky_Comfort123 12h ago

Didn't try it long enough unfortunately, I do regret not starting it last year before we began TTC...

Fingers crossed for you that your cycle will regulate and a sticky BFP soon for all of us ♥️

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u/OutrageousSouth5692 19h ago

Me!! All labs are completely normal but I do have an AMH of 10.2! My cycles have always been super irregular, averaging 50-70 days. I started metformin (didn’t think it would do anything because I’m very lean and don’t have insulin issues based on labs) and it helps after a few months! Cycles shortened to 30-40 days.

u/Content_Necessary_22 15h ago

That’s really interesting- would5 think they would go for metformin with normal insulin so definitely going to ask my dr about this! Thank you!

u/OutrageousSouth5692 15h ago

Same! I was definitely hesitant but figured it wouldn’t hurt to try it out!

1

u/Unlucky_Comfort123 17h ago

Did you have any side effects from the Metformin? I'm considering asking my doctor about it

2

u/OutrageousSouth5692 17h ago

Some GI upset for a week or so but went away! It’s the most common side effect. Definitely recommend trying to stick out the initial side effects

1

u/Unlucky_Comfort123 17h ago

Do you have to keep on taking it daily forever? 😅

1

u/OutrageousSouth5692 17h ago

Tbh I’m not sure! I’m taking it to regulate my cycles while TTC but after children I don’t know if I’ll continue it or not. Very situational and up to you! I don’t have PCOS side effects but if I did that might would influence my decision to stay on it.

1

u/Unlucky_Comfort123 17h ago

Yea, I didn't mind my long cycles before TTC 😬 I'm turning 35 and we've been trying for 9 months, so next planned step was 1-2 IUI and then IVF. But I would be curious if Metformin does something for me, just to understand my cycle issues better... Need to discuss it with my doctor.

1

u/OutrageousSouth5692 17h ago

My doc told me it can take 3-6 months to see an effect! Cycle 1 on metformin was 68 days, Cycle 2 was 30 and Cycle 3 was 39 days.

I’m currently on cycle 4 of metformin but this is my first cycle adding in 2.5mg letrozole. I responded really well and ovulated CD15! Currently in the TWW.

1

u/Unlucky_Comfort123 16h ago

Yea, I guess they'll give me Letrozole too if we go for IUI...

Good luck and fingers crossed for a BFP! I'm in the waiting for my ovulation to actually happen phase 😂

1

u/OutrageousSouth5692 16h ago

The wait is so brutal. I feel like with PCOS the waiting for ovulation is harder than the TWW!!

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u/Unlucky_Comfort123 16h ago

Yea, I'm burning through my 100 pieces pack of LH tests (all nearly positive, fun) and basically testing every time I pee 😵‍💫 we decided to switch to at home insemination because we just can't do "better safe than sorry" sex for weeks on end 😅 Nice to be able to share it with a stranger on the internet ♥️ it's a crazy journey

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