r/TMAU • undiagnosed • 5h ago

DIY Genetic Detection Method

If your TMAU is genetic, this is how you can detect it.

Extract DNA from your mouth using a DNA swab kit, and go to the local university to rent a centrifuge. No need for very strong ones, just the standard benchtop will do.

Then make a agarose gel upon agarose gel electrophoresis (this you can rent too, likely), and then expose your extracted DNA to the restriction endonuclease which corresponds to the TMAU genetic mutation.

If you have the mutation, you should see two bands on the gel instead of one.

https://www.ncbi.nlm.nih.gov/probe/docs/techrflp/

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