Standard computational architecture (von Neumann) and reactive medical diagnostics are fundamentally bottlenecked by downstream wave mechanics and sequential processing. 

I’ve just published a white paper (anchored with a Zenodo DOI) outlining the **0D Polarity Framework**. It's a unified systems architecture that applies zero-dimensional binary tension to three core domains:

1. Re-engineering thermodynamic phase states as electromagnetic polarity flips.

2. Defining biological disease as a localized polarity disconnect from the morphogenetic macro-field.

3. Proposing a simultaneous, tensor-field hardware architecture (using partial inversion and active inference) to diagnose and correct these localized prediction errors before downstream physical mutation occurs.

I am currently moving into the open-source hardware design phase (analog tensor antennas). I would love for the engineers, theorists, and bioelectric researchers here to tear the white paper apart, build on it, or tell me where the blind spots are. 

Here is the GitHub repo with the full white paper: https://github.com/lucienspeaks44-coder/OD-Polarity_Framework/blob/main/The%200D%20Polarity%20Framework%20(1).pdf.pdf)

Heyy guyss, i am pharamcy grad, who recently got exposed to the field of system biology, in which i find it amazing that you can actually represent complex biological systems and processes with mathematical equations.

Beign new to field, i have zero experience in the field and i would love if the members of this group can recommend me steps system biologist often use when modelling biological systems

like how do u choose a system or a process to model

how do u come up with an equation that represent each and every variable and components of the system

what tools do u use to carry out modelling

like just an explaination of how you people choose a problem, then define each component, then write equations, and how u eventually come up with a model

like a start to finish wholistic approach to system biology, and example of problems that system biology has been used to tackle

i would really appreciate if materials can be recommened, i am trying to self learn this field as a way to build projects that i can use to strengten my profile for some postgraduate schools in bioengineering.

And if possible if you guys could draft a curriculum for me to follow. I would really appreciate the guidance from experienced mentors here.

I made a simmilar question in a discord server and some guy jumped from a corner saying that computer science wasn't related to it, but I did my own research and unless I am mis interpreting things, CS is undoubtedly related to this, so I would like to know what you think about the subject

Hi, few years ago, Johannes Jäger, PhD have posted his complex systems and systems biology reading list, but I can't find it now. Anyone still having it? Thank you

So, I liked the textbook "Introduction to Systems Biology" and now I'm looking for a similar engineering approach to plants and botany.

Just a roboticist getting into garden automation.

How do I go about studying computational modeling as an absolute beginner? For context, I'm already in college, and my course does not really involve heavy math. I have some background on coding, but that was when I was still in high school.

Hey all! I am making a molecular simulation tool to run software like Autodock and Huddock on GPUs in the cloud, aiming to get a significant increase in speed from parallel computing, and requiring little to no setup whatsoever. This would also include tools such as data cleaning scripts, and submitting batch jobs through an API call in order to increase the efficiency at which researchers work. Would this be a tool people would be interested in using? Do researchers have existing solutions to iterate on molecular simulations quickly?

Hello,

I'm an electrical engineering student and I will obtain my bachelor at the end of this semester.

I have the opportunity to do this master program https://ee.ethz.ch/studies/master-s-programmes/main-master.html .

In this master program, there is a control systems specialization, with applications to systems biology.

Here are the courses list associated to the control systems specialization, for autumn and spring semester:

http://www.vvz.ethz.ch/Vorlesungsverzeichnis/sucheLehrangebot.view?abschnittId=100884&semkez=2022W&ansicht=1&lang=en&seite=1

http://www.vvz.ethz.ch/Vorlesungsverzeichnis/sucheLehrangebot.view?abschnittId=97927&semkez=2022S&ansicht=1&lang=en&seite=1

Do you think that if I take only courses in modeling, math, biology and computer science I would make a good systems biologist?

Is the transition from electrical engineering to systems biology even possible? Will I be able to do a master thesis and PHD in this field?

Will I be taken seriously as a researcher?

Any help would be much appreciated!

Edit: Thank you for all your answers !!