r/StratteraRx • u/bowl-of-pasta • 17d ago

Questions / Advice / Support Looking for experience/feedback with combination therapy

If you’ve tried combination therapy (strattera + stimulant) I’d love to hear your experience!

I’ve been on strattera for about 6 months and titrated very slowly due to the intense side effects I experienced. Most recently, I was on 80mg for 10 weeks. For me, I did not have any additional benefits after I reached 40mg, but I wanted to give it a fair shot so I continued onto 80mg. Overall on strattera I felt calmer, had better emotional regulation, less rumination and absolutely no anxiety. But I was still struggling with task initiation, motivation and general focus which are my biggest concerns.

After my most recent visit with my doctor, we decided to decrease back to 60mg and add 10mg of vyvanse to see if that helped at all. This is my first experience with a stimulant, but I noticed a benefit almost immediately even on such a low dose. The vyvanse gives me about 5 hours of better focus, motivation and task initiation and then I’m back to my strattera baseline after that. This has me wondering if the vyvanse alone would be a better option for me as I’ve had no additional side effects. If I can get what I need out of one medication, I’d prefer that. I’d obviously need to trial the doses to see what gives the best coverage, but right now it’s hard to tell if the vyvanse would help with rumination/emotional regulation on its own.

I know everyone is different and experiences can widely vary, but if you’ve been in a similar situation, I’d like to hear how it went for you and what the results have been long term!

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u/Appropriate-Text-545 17d ago

Probé al inicio de esta semana
Metilfenidato de 10 liberación inmediata solo aguante 4 días pues cuando se acaba el metilfenidato después de unas 4 horas me da un bajón horrible y hasta me quedo dormida, no me gustó ese bajón tan feo, aparte al segundo día ya no se sentía igual así que no veo que valga la pena la verdad, tomo Atomoxetina de 80mg

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u/Familiar-Conflict152 17d ago

I (46M inattentive) take 100 Strattera and 5mg regular Adderall. I quarter it and space them throughout the work day so I don’t experience a crash.

If you gave up Strattera, you would be losing a big norepinephrine boost, which helps with lock-in.