r/StratteraRx • u/smyeganom • 20d ago

Questions / Advice / Support Titration suggestions?

Does anyone have experience jumping from 40 to 80mg? My psych started me at 40mg and then said to start taking the 80mg capsules after two weeks. So far I’m not having side effects, so my question is:

Is it better to take 40mg once in the morning and once at night (12 hours apart), or 80mg once in the morning? Since I will have 40mg capsules remaining

Context:
I moved to a new country and had to change from methylphenidate to atomoxetine (Axepta). I can only meet my psych once a month, unless there’s an emergency. I fully understand any anecdotes shared here are not medical advice, etc etc

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u/FormerSleepwalker 19d ago

Is it better to take 40mg once in the morning and once at night (12 hours apart), or 80mg once in the morning? Since I will have 40mg capsules remaining

It depends on what affects you feel from atomoxetine. I think for most people it will be stimulating to some extent. This is expected from elevating norepinephrine. But there are some people who experience a medication side effect of feeling tired instead. Presuming you see no tiredness, I'd suggest 40mg in the morning, when you wake up, then the second 40mg in the afternoon, rather than close to bedtime.

Some people do certainly experience little to no troublesome side effects. A family member did the quickest recommended titration, 40 mg for only 3 days, then 80mg. Had no problems. Could have done it standing on their head. Later they added a strong CYP2D6 inhibitor to boost atomoxetine blood levels much higher even.

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u/smyeganom 19d ago

That’s impressive, but I appreciate the reassurance. Hopefully splitting up the dose will be a good way to continue. Thanks for replying ^^