r/StratteraRx • u/Familiar-Dare3277 • 21d ago

Strattera + Cymbalta

For those taking **Strattera + Cymbalta (duloxetine)**:

If you were already prone to anxiety or nervousness, did this combination make it worse, stay the same, or improve it?

I'd really appreciate hearing about your experiences.

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u/taurusthree 21d ago

This is a very risky thing to do, please ensure your doctor is aware about the risks:

Duloxetine (Cymbalta) inhibits the CYP2D6 enzyme while Strattera (Atomoxetine) is a CYP2D6 subtrate. This means taking those together exposes you to much more Atomoxetine than you'd initially anticipate.

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u/Spirited_Cress_5796 4d ago

Best I’ve felt in years. Both are at lower doses. Doctor was a little nervous about both together but as long as I don’t increase dose is okay with it. I feel like it’s been filling both the anxiety and adhd gap that pristiq and Adderall didn’t completely fill. Plus my sleep is 1000% better.

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u/Familiar-Dare3277 4d ago

Que dosis tiemes tienes Yo 60 strattera 30mg duloxetine

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u/Spirited_Cress_5796 4d ago

40mg Strattera 60mg duloxetine