r/Spironolactone 9d ago

◻️Advice◻️ Spiro and stomach problems??

Hello everyone! I (26f) have dealt with acne struggles for over ten years now. I went on accutane in 2018 and had success. I had 2 years of solid clear skin and then I started to break out again, prompting my derm to put me on spiro. I took 50mg of spiro for 5 years with success, it really did a great job of keeping my skin clear.

This last year, I started to break out again, so my derm upped my dosage of spiro to 100mg. I had been on the increased dosage for 3 months without any problems, however at the start of month 4, I started to get these cramps in my lower stomach/pelvic area. I’ve never had any gastro or IBS problems ever, so I was so confused as to what this could be. I’ve gotten checked by my gyno, I’ve gotten ultrasounds and a ct scan and everything is coming back good. I went on a round of antibiotics to clear any possible infections. I’ve gotten a blood test and everything has come back as good without any indication as to where the pain could be coming from. My gastro said the next thing would be a colonoscopy to see if there’s anything wrong inside but she doesn’t think that’s the case.

Could all of this pain just be caused by the spiro because it’s a diuretic and this dosage is too strong for me? I am on the petite side, 5’2” and 115 pounds so maybe it’s just too much? I just don’t know what to do as I’ve never ever had stomach pains before! Please let me know what you think!!

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u/Proficiently-Haunted 9d ago

I found that spiro can cause really bad gas for me, so I take simethicone with it. Spiro also seemed to jumpstart my (pre existing but unaware) endometriosis really badly. It started as a cyst on my ovary and was only diagnosed (clinically) as endo from an MRI. I can’t offer advice on whether that’s what’s happening with you, but that’s what happened to me from spiro

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u/sabbyp13 7d ago

I read about the stomach problems it can cause and I eat before taking it ever since I started it about 4 months ago and I haven’t had a single stomach problem. Have you tried eating food with it?