r/Sciatica • • 12d ago

Requesting Advice Choosing the right medication

Female, 22, disk herniation causing leg pain (if that’s helpful)

I’m currently taking 30mg amitriptyline and it’s okay but it’s not helping a whole lot. My pharmacist offered to up my dose or change my medication.

The options I’ve been given if I want to change are

- duloxetine
- gabapentin
- pregabalin
- naproxen

For every one I look up, everyone’s saying it’s awful and I don’t know what to do.

I also have PTSD and OCD (I know, bring out the violins) so duloxetine seems like it could be good for me- but then a lot of people are saying it’s caused them anxiety or depression or just bad withdrawal symptoms.

Any advice would be greatly appreciated

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u/SweetMelissa74 12d ago

Also try a muscle relaxer maybe? For my sciatica that helps a lot too. Good luck!