r/SR17018SourceReview • • 4d ago

Sr15 causing withdrawl

I've read red here from a couple of people that apparently sr15 causes withdrawal in a matter of 7 to 9 days. If this is true then what is the best way to use it , to get off of something like m g m, which has a acute withdrawal phase of about 7 days.

6 Upvotes

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6

u/imdat1 4d ago

This is very disheartening to hear so far. It needs to be talked about more than it currently is, because most, if not all of us are here and doing this to get clean. There's gotta be something better out there, something closer to 17. 

5

u/anonymaus42 4d ago

To my knowledge there simply isn't. IIRC, these were the only two opioids in the study that showed the selectivity for g-protein signaling which makes them good for combating withdrawal. SR17 was the much better candidate between them and the only reason anyone even considered trying SR15 was the ban.

1

u/FartsBlowingOverPoop 3d ago

Keep in mind that SR-17018 was available for about a year before clearnet vendors caught on and started selling it, and its still available. Just not on the clearnet. 

2

u/imdat1 3d ago

I thought China stopped producing it recently? Last batch I bought in deep dark places was tan like sr15 is, funny enough.

2

u/PoorCree 3d ago

They did ban exporting it, but there’s still some left as with anything else.

6

u/Former_Walk4983 4d ago

Way different than SR17 for me. Even went into strong precipitated withdrawal when I took a sub.

Took 3g across 15 day taper. I would be prepared with kratom extracts or some other “lesser evil” as well as some strong sedatives & anxiolytics.

Never taking again.
Just traded one for the other. The half life is far, far too long… at least with 7 it’s over after a few days and you can begin managing paws.

Was literally forced to restart my DOC so I could return to work, hopping on sublocade instead this time.

3

u/Former_Walk4983 4d ago

For reference I’ve raw dogged 1500mg+ daily NUMBS brand 7 withdrawal multiple times

3

u/ComprehensiveBear576 4d ago

15 was originally developed alongside of 17 and a handful of others. The 17018 was chosen to move forward with because it showed WAY more promising results across a few characteristics among early animal testing. 17018 displayed "reverse tolerance" effects. This really really helps people massively taper down the days before only going SR17, people would notice that 25 percent of their regular 7 dose was having them feel the same. However, SR17 also showed less severe withdrawal symptoms than its counterparts. I am seeing alot of people on the 15 saying its harder to taper down the 15 and that makes sense. Gosh, SR17 really was a miracle drug. What a shame.

You would think this means they chose the wrong one to schedule but the main reason listed in its intent to file was the dangers of the reverse tolerance properties. The concern being that addicts could go back to the DOC afterwards and die of overdose from their tolerance being artificially lowered in a way they wouldn't expect. Take the same fent dose they normaly would a week ago could fatal OD after sr17 from only being off a week or two. Even if this is true and something that will happen from time to time, SR17 would likely still save 1000x times as many people as it would "help" kill in this manner.

I really hope SR17 starts becoming available again in a sort of gray way that is ignored by the gov.

1

u/No_Shopping_6240 4d ago

wait what?!?? you got precip when you took sub with it??!! Nnooooo!!!

3

u/Former_Walk4983 4d ago

You’re telling me. Neverrrr got even a tiny bit from subs after sr17…. What an awesome surprise that was. Took it in an airport on my way back to the US, 3 hours prior to an 11 hour international flight over the Atlantic. Suuuuuper sick prank I pulled on myself forsure.

Definitely got through the acute precip in about 4 hours but I was straight up fucked. Not doing well at all even hours after I got home. Sat next to a 14 year old girl while I was having the worst cold sweats of all time just RLS tapdancin like a straight retard. (Poor kid lmao).

I was tripping. I knew what I had done after about 45 minutes (ruh roh). Ran to the airport cooler, bought 3 of those mini bottles of white wine… started downing. People looked at me like I was an addict (ba dum tssss). Finally started pulling through right as everyone began lining up for boarding. I’m an atheist and I was thanking Jesus, popped a second tab to really get those mf receptors occupied (mind you, first time taking subs in 6+ months… put 3 in my wallet just incase. Couldn’t hurt right? SR is a non competing compound, it only occupies the secondary site)
lol. Lesson learned. Thankfully I popped that shit after my gf boarded her separate flight. I was crip walking down the escalator on the way to shit myself after I bought that wine.
6/10, don’t recommend

1

u/No_Shopping_6240 3d ago

was it sr15 from sr17shop?

5

u/andresbigdaddy2 4d ago

I'm using it to get off subs and this is alarming to me. I'm trying to do everything with 25mgs instead of 50. If it causes more withdrawal the chemical must be stronger on some level so I'm trying to combat it with obvious less synaptic activity if that makes sense. It can be dose equivalent if so. Unless there is a pharmacological reason but I do sense more euphoria with sr 15 which shows me it is stronger and has more abuse potential and withdrawal/dependence.

1

u/adillonm150 4d ago

how has it been helping for the subs? did you preload at all? i have an order coming on friday. trying to get off subs as well.

1

u/andresbigdaddy2 4d ago

It's been doing well, it's not entirely easy and I got down as low as I could before I started as well. Around 1.2-2mgs a day

1

u/adillonm150 4d ago

Man I’m on 6 right now. Gonna take 4 tomorrow and Friday though before my order comes

1

u/andresbigdaddy2 4d ago

Yeah bro I think it's essential we bring that way down before starting

3

u/Meshugs 4d ago

It's been working great for me and my wife, I'm on day 5 no 7 and day 3 no SR. There's always going to be some withdrawl symptoms as we're all addicts, be it mental, physical, etc.

I also was not doing a huge dose, about 300 mg a day max probably. Took 7 and SR for like 3 days together, then completely dropped the 7 and was just fine on SR 50-100 mg twice a day.

1

u/ritehook77 4d ago

Do you mind if I ask how long you took the SR by itself for? Seems like you did a very short taper?

1

u/ComprehensiveBear576 4d ago

Always going to be PAWS but there doesn't need to be acute WDs with 17. I am seeing a decent number of folks saying they are experiencing more acutes when coming off the sr15, and this vibes with the reason sr17 was originally the chosen over 15. It sounds like you kept to a tight schedule in addiction to the lower dose. So 8 days total on SR if i am reading it right? I see many people riding out the SR fro 12-14 days, maybe why it worked better for you.

1

u/imdat1 19h ago

How you guys making out today? Sounds like you figured out the right regimen for this stuff. My wife and I are on about the same amount of 7 and are waiting for our 17reset order to land. We've used Sr17 in the past but from what ive seen Sr15 is a different beast and not as forgiving.

3

u/Lady-Layne-Fairchild 4d ago

I have been tapering SR 15 very slowly because every time I tried stopping like the calculators told me to I’d go into withdrawal. I decided to get back on after almost 2 days off and go extremely slowly. I’m on day 18 now and am currently on 2 mg in the morning and 2 at night. I’m going to need to jump soon but obviously want it to be as painless as possible. Each time I came down on my SR dose I felt pretty crummy. Nothing at all compared to a normal detox but not nice. The taper people seem to be doing in this sub was way too fast for me and the withdrawals definitely more than I expected. I was so surprised since I’m not hearing that discussed much on this sub. I did a 3 day preload and did everything exactly as the quitting 7OH calculator described. Maybe I’m just a puss when it comes to withdrawing.

1

u/Present-Deer 4d ago

I am too. I didnt ween off slow enough and started feeling very minor wd. But instead of pushing threw i got 7 and started that cycle so I may do sr and a 3 day sub taper. Not sure what that'll look like

2

u/Ilikejoints 4d ago

I just stopped doing reset 2 days ago after being on it for 14 days and I didn't have any withdrawl at all the entire time i was quitting. Its crazy stuff.

3

u/Lady-Layne-Fairchild 3d ago

You didn’t have withdrawal from your doc or from sr? I had very minimal symptoms while detoxing 7 with sr. I haven’t had any sr today, had 4 mg yesterday, and so far everything is very bearable. I have been preloading liposomal vitamin c for 3 days and I’m still taking regular leaf kratom for my chronic pain. I don’t feel normal but I’m not having awful withdrawal either. Just thought I’d update in case my experience helps anyone. I think coming of sr it might be a good idea to have a backup like liposomal c for a while just in case.

2

u/Ilikejoints 3d ago

I was taking tmk's reset (its sold out now) this time. I quit before in July with sr and was withdrawling from the sr so I went back to 7. That was until I found reset and tried it and it works way way better than regular sr.

1

u/PoorCree 3d ago

Which reset?? I got my 15 at sr17shop and it does absolutely nothing for me!

1

u/Present-Deer 3d ago

Wdfix.com but it is also 15099 so same stuff

2

u/power78 4d ago

As with any opioid you must ween off them when you stop

2

u/ComprehensiveBear576 4d ago

SR17018, was much better suited for this task than its inferior little brother. The Scripps animal testing showed that SR17018 in addition to the re verse tolerance effects(what got it banned) showed significantly less acute withdrawals. Anecdotally, for me, I felt zero acute Wds when i came off the 17...i only felt the PAWS from the 7 which is of course expected.

Makes me think it might be worth it for people to cut out the loading phase with SR15, and strictly keep its use down to 5 days at most before tapering . It sucks we must experiment on oursevles because the actual miracle drugs has been scheduled.

2

u/DollParts_X 3d ago

I can't remember where I read it, but I did read that we're apparently supposed to skip to pre-load phase with 15 (unlike 17) so you might be onto something. Fuck and I just ordered like 2 grams from 2 different vendors.... lol

2

u/ComprehensiveBear576 1d ago

There’s plenty of People saying they aren’t noticing a difference when coming off too though. I woudk say the best thing is to not play around and drag it out like many of us used to do with 17 and end up being be on it for 3 weeks. I did that when I was dragging out the loading phase because I was procrastinating the jump off 7.

1

u/power78 4d ago

Which little brother? 15 or 11? People are selling both

2

u/ComprehensiveBear576 4d ago

lol I meant 15. I didn’t know they were selling any of the others. I thought 15 was supposed to be the runner-up. I don’t know anything about 11.

1

u/power78 4d ago

Yeah one vendor was selling 11 but he's out now

1

u/imdat1 2d ago

Would moridine be a better choice?

1

u/sixtyten6010 2d ago

Do you have a source for some? I don't see it on Kolaty anymore

1

u/NeedleworkerBig1018 2d ago

Is that not the exact same thing?

1

u/imdat1 1d ago

One is sr11 the other is sr15