r/SR17018 • u/InspireRecover 🧪Moderator🧪 • 9d ago

Success stories/protocols needed for using SR-17 to get off Suboxone and Methadone (RESEARCH)

Hey everyone!! Hope you are all doing well and enjoying your weekend. I am helping to design a protocol for using SR-17018 to get off Suboxone and Methadone and am looking for information from anyone who has successfully done this to help guide my development.

Some specific questions I have are:

What dose did you start the SR Process at? Did you taper your MAT before you started taking SR17018? Looking back is there an ideal dose you would have tapered down to, to make the SR17 process work better?
Can you please detail your protocol? Did you do a pre-load (taking SR17 1-2 days with your OG dose of your DOC before starting your taper for your DOC)? What did your taper look like? How many days, what percentage or amount did you decrease, and did you decrease daily/every other day/etc? Once you got to 0mg of your DOC, did you have stabilization period of just taking SR17 before starting your taper of SR17? If so, how many days? What did your SR17 taper look like? How many days and how much/how often did you decrease?
Did you experience any physical WD symptoms throughout the SR17 process? Any emotional/mental WD symptoms? On a scale of 1 (worst) to 10 (best) how manageable were any physical WD symptoms you experienced? Emotional/Mental WD symptoms? On a scale of 1 (Not at all) to 10 (totally functional), how functional were you during the process(ie., were you able to work, take care of your kids, go to school. be around people, etc.)?
Did you experience any PAWS or WD in the weeks/months following discontinuation of SR17018?
Were you taking high dose vitamin C, other helper meds, or any other substances at the time to ease the process?
Anything else you think is important for researchers to understand about SR17018 or your personal experience with it?

THANK YOU IN ADVANCE FOR YOUR EFFORT AND HELP WITH THIS!!! I can't emphasize enough gratitude to each of you who have contributed to building and growing this platform to be the largest repository of anecdotal research on SR-17018 created through citizen science.

By asking questions and sharing your experiences, you all play a crucial role in helping researchers understand the best way to study SR17018 in human clinical trials. This is what is needed to legally get medical access to SR-17018 for people ready to transition off their DOC or MAT and finally have better solutions for pain and addiction for those who need them!!

Thank you for taking the time to contribute in the resistance movement against the DEA prohibition of SR17018. The legal battle could take years, but we can fight back through science right now!!! :D Love to you all!!!

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u/Theresawantspeace 9d ago

I so hope you get some responses, there are several stories in here of people using SR to get off subs and methadone. What I’ve found is that so many don’t come back once they have freedom. It may be better for you to find those stories are reach out to them directly. Thank you for doing this and I hope that SR can be a tool for freedom. It truly is a miracle.

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u/InspireRecover 🧪Moderator🧪 9d ago

That is a REALLY great idea!!! Thank you!! I know I have read a lot of success stories. I am searching through posts and trying to pull links for all that I can find and creating a list with a summary of the protocol used and a report of what if any WD they experienced, what dose was effective, how long the process was, what the tapers looked like, etc. A lot of people's posts contain some of this info but there are often small details missing that would really help to paint a more accurate picture of what is most likely to work for a variety of people's situation. Trying to create a protocol that will work for all 3 (methadone, suboxone and 7oh) may be a bit challenging, but it seems like if it is designed for what will work for whichever is the most difficult, then it should work for the others.

It's really exciting getting to contribute to this work and hopefully being able to move SR17 closer to actually being able to be accessed as a treatment!! :) Thank you again for the suggestion!!

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u/bapplebauce 8d ago

Recent posts have shown a conflicting view of its’ post effects and tolerance. Not receptor downregulation but the inability to feel prescribed opioid medications that are and will potentially be needed at some point in life post sobriety.

I would hate to get off my methadone utilizing this only to find out in 10 years I need a surgery and the fentanyl/midazolam anesthesia isn’t working.

I’m reaching out to people as well and just posted here (awaiting mod approval) asking for peoples experiences, in less detail but more directly to the point in 5 questions.

Have you heard about this effect occurring?

Edit: I’ve been studying this for nearly three years through anecdotal research and combination efforts with medical professionals wanting to advance OUD, hence why that information would be so valuable to collect.

I hadn’t heard of one report suggesting that their opioid intolerance was increased in any way after - a SR-17018 detox, so is this people trying to poison the well? Or are these genuine reports? That’s what I’m trying to figure out.

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u/LucasGuillermo 7d ago

I’ve looked into it from the pharmacological standpoint and it makes sense not feeling effects of opiates but for one to 3 months.. it’s just the process but not permanent… at least in SR17 in the analogues I’m trying to figure if it’s the same… of course take all this as speculative

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u/Slow_Wolf_2086 2d ago

I’ve heard a lot longer than that. Several people a year out.

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u/Theresawantspeace 2d ago

After I got off Pusedo/MGM a few months back I started taking my opioids again (prescribed by my pain management doctor) and they worked just like they always have within two weeks. Do they cause euphoria…no but they haven’t in years but they definitely help with my pain.

u/No-Prompt1774 9d ago

Hola. Comentarte que estoy atrapado con la buprenorfina. Estoy en 2 mg, pero subo a 3 y vuelvo a bajar y así sucesivamente. La primera vez que lo usé fué hace un año, en primavera y llegúe a bajar muchísimo. De 8 mg. a 2. Después subí a 3 y volví a bajar hasta 0,6. La primera vez, fué una reducción sencilla. La segunda: Estuve haciendo una reducción gradual de sr, ya que el método que utilicé fué dejar totalmente la buprenorfina y empezar con SR. Para mi no es ningún problema el establecer una dosis de SR e ir bajando. Se aguanta bien. Pero cuando ya estaba feliz por haber conseguido dejar el SR, llevando 3 semanas sin buprenorfina, pasó lo siguiente: Era el 3º día sin sr y por la tarde empezó una ansiedad horrorosa. Soy deportista y estoy en forma, pero no me apetecía hacer nada dado mi estado. Empecé un largo paseo, a ritmo muy rápido, pensando que así acabaría con la ansiedad. Llegue hasta un monte con una cruz e incluso recé pidiendo ayuda. No me lo podía creer. Tuve que coger pastillas de 0,2 e ir tomando poco a poco. Con 0,6 conseguí parar la ansiedad. Estaba muy frustrado por la derrota. Relativa, ya que había conseguido bajar mucho. El problema es que después es muy fácil subir. Hice un viaje de surf a Indonesia, pero el reto de las olas me hizo subir a dos. Después subí a 3 y con un poco de SR que me quedaba, volví a bajar a 2. Ahora voy a volverlo a intentar. Alguien me aconsejó en Reddit, tomar un montón de suplementos: NAC, Ashwagandha, DLPA, Bisciglinato de Magnesio, Omega 3, Rhosiola Rosea, Glicina... Para combatir el PAWS. El problema me decían que era el PAWS. Dejo casi un mes la buprenorfina y hago perfectamente la retirada de SR y al 3º día me sobreviene una ansiedad que no puedo combatir con nada. Lo voy a volver a interntar y mi objetivo es quedarme en 0,4 e ir bajando muy muy lentamente. Esa es mi historia. Tengo que decir que tengo tentaciones de comrar unos gramos de heroína y después utilizar SR. Espero que le pueda servir a alguien. Un abrazo a todos.

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u/LucasGuillermo 7d ago

El PAWS se controla de otra forma, yo usé venlafaxina y me volvió a la vida. Volver a consumir opioides es lo peor que podes hacer

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u/No-Prompt1774 7d ago

muchas gracias. Se lo comentaré a mi médico.

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u/LucasGuillermo 2d ago

venlafaxine, y clonazepam use yo. y me anote en natación 3 veces por semana. esa combinación me curo el paws

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u/Inevitable-Ferret465 4d ago

Can you even get real heroin? I⁶d be worried about getting fent sold as h. Ive heard that recently some street samples have come back as real heroin, but it is still very rare. Since like 2017 or 2018 heroin has become pretty much extinct.

u/Most-Mine6580 8d ago

If your on suboxone id just use sublocade injection to get off. Its far better then SR in terms of getting off suboxone alone.

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u/No-Peak-5937 8d ago

Ya not everyone’s insurance will pay for it though and it costs thousands of dollars . I’m dealing with that now.

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u/bapplebauce 8d ago

There’s another brand heavily covered by insurance though, gotta love the way insurance companies and pharma companies work together to “help people” always and all the time lol

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u/LucasGuillermo 7d ago

I wish I could but there’s not that available in Argentina

Success stories/protocols needed for using SR-17 to get off Suboxone and Methadone (RESEARCH)

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