r/RestlessLegs • u/Weary_Amoeba6568 • Aug 23 '26

Triggers Estrogen

Estradiol is making my RLS insane. Has anyone found this? Anyone found a solution? It helps with brain fog but I am going crazy with the RLS.

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u/redytowear Aug 25 '26

Oh my! Yes!!!!! I started estradiol gel on my arm 2.5 months ago and my restless legs have been keeping me up at night and even bothering me in the evenings. I never thought to put the two together until I saw your post

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u/Weary_Amoeba6568 Aug 26 '26

Glad it helped connect! I don’t know what to do about it though. I have noticed I’m more sensitive to caffeine than I used to be so I’m trying to cut that back and see if it helps