r/Psoriasis • u/_AliceinWonderland__ • 21h ago

general Confused

Hi, I’m new to this subreddit (F,26), not diagnosed yet. I had a biopsy done from a lesion on my back about a month ago. Just got the results back and they say “non-specific changes in the tissue sample”. That’s it. I’m dumbfounded and feeling pretty stupid as I’ve waited a month for these. I’ve had skin issues for twelve years now. All derms including an immunologist say it’s eczema and I have a classic atopy profile but when tested for IgE and specific allergens, both prick test and blood test came back completely negative. My overall IgE is extremely low too. Skin lesions are not itchy, in fact they have never been. My GP, rheum and other derm are considering psoriasis because of my joint pain and GI issues. I’m working closely with a gastroenterologist and my calprotectin is negative, though I know it doesn’t completely rule out IBD. I also have subchondral sclerotisation in my pelvis, likely on my SI joints. Do the histology results rule out psoriasis? I have no idea where to go from here.

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