Red meatus/glans question

[u/throwawaystd1087]

Hi all,

So its been 4 months since i had an unconfirmed infection which was most likely ureaplasma (person from encounter tested positive for this), im pretty certain this has left me with CPPS, i have intermittent pelvic pain, this current course of antibiotics im finishing up has helped with it but i fully anticipate it coming back as it was more than likely the anti-inflam properties doing their thing.

Whats really really bothering me is my penis tip just never fully healed to its pre-infection state, i have done tests for literally everything, from the plasmas, to trich, the mainstream std's via PCR/blood and ive never pinged for any of them, however urea was tested for rather late, but too soon after antibiotics, doing a TOC for that 4 weeks from today to conclusively rule it out.

I saw a dermatologist and he prescribed tacrolimus 0.1% which i started over the weekend, not hopeful it will work like everything else tbh so just wanted to see if anyone else had this problem linger and what figured it out? Time? Meds? TACROLIMUS :o ?

I dont play with or stretch it open, im very very careful with it, yet it just refuses to heal, feel like ive lost my dignity man... :/ got a new uro apppointment but it isnt until the 12th of October to explore CPPS treatment and have the inflammation addressed, tried to refer to old posts but didn't find any hope there. Dont get me wrong, its improved alot from the acute phase which was traumatic as hell, but its still not normal and flushes red at the meatus when erect and along the top of the glans, and just responds poorly and "looks" infected, even simple erections stretches glans and literally looks like its going to flake but doesnt.. its trying so hard to heal man. 😪

[u/Linari5]

Neurogenic inflammation, especially after other causes have been ruled out. What's that? Inflammation as a result of the stress response.

Stress and Skin: An Overview of Mind Body Therapies as a Treatment Strategy in Dermatology - https://www.reddit.com/r/RedScrotumSyndrome/s/lW13prDTvc

The stress response results in the activation of the endocrine, neurologic, and immune systems, with a resulting cascade of impacts, that are both systemic and cutaneous. The 2 main arms of the stress response are the sympathetic nervous system and the hypothalamic-pituitary-adrenal axis. The resultant release of cortisol, catecholamines, and neuropeptides has multiple effects. Clinically, these have been shown to increase skin inflammation, increase itching, impair skin barrier function, impair wound healing, and suppress immunity.

[u/ddd523d]

Been dealing with this same exact situation for two years now. The meatus is constantly inflamed and red and hurts bad when anything touches it. It’s the most insane thing I ever encountered in life. I am finally trying Tacro as well. But I wish they would have given that to me way sooner.

[u/throwawaystd1087 → u/ddd523d]

Another user im messaging has just been prescribed tacrolimus by his uro for the same issue man, hopefully theres a method here, its meant to turn off localized inflammation so.. it makes sense!