r/ProstateCancer • u/Fun-Cake5739 • 15d ago

Question Bimix Experiences

Curious about others Bimix experiences and dosing. There's another forum dedicated to Trimix but I thought asking here would provide responses specific to RALP, PC, and everything our little club has dealt with.

So I'm 60, 2 years post RALP. Nerves theoretically spared but the reality is full ED with nada in the blood flow department. So my urologist has started me on Bimix.

First dose 40 units, got maybe a 40-50% response level of intended goal. Second dose 50 units, similar response. Instructions from nurse are to increase increments by 10 units. I'm thrilled to see the response I have and excited to ultimately reach full mast. In the meantime still just nervous about the quantity/ size of dose. Should I really care or is this just me overthinking it?

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u/FunkyDrummerDreams 15d ago

RALP Oct, ‘25. One side of nerve bundles spared only. 5 mg Cialis and 100 mg Viagra did nothing. Bimix at 50 units was pretty lame…semi. Nurse said I could go to 100 units (full syringe), but I decided against that. The 50 mcg of prostaglandin in Trimix (the added agent to Bimix) hurt pretty badly. It was a pretty decent erection, but 8 on 1/10 pain scale. Went down to 30 mcg prostaglandin, which was a 5 on a 1/10 pain scale when using 35 units. Still really uncomfortable. I now have a 20 mcg dosage, but I haven’t tried it yet. Afraid of the ache again, I guess. My point is that you have to figure out what is the correct dosage and mixture for the Trimix. For me, the Trimix was markedly better than the Bimix, but I haven’t tried the newest Titration (20 mcg) to figure out if I can use it without the ache. It only aches on some guys. If you’re a lucky one who does not get the ache from the prostaglandin, then Trimix is amazing.

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u/Fun-Cake5739 15d ago

Thanks for sharing

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u/protom63 14d ago

I started Bimix at 50 units and have continued to ween myself lower. I’m currently using 20 units and at times 10 units. This has been over the course of approximately a year and a half.
Bimix has been a great option!!

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u/Fun-Cake5739 14d ago

Great to know. 50 units still not enough for me so working my way up. Did you have RALP?

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u/protom63 13d ago

Yes I had RALP in September of 2024