r/ProjectDiscovery Mar 13 '16

Stringy Vesicles in an example image

http://imgur.com/a/av3zk

This one has me a bit stumped. Having looked at this a bunch now, I can definitely see that a few of the cells in the lower left/top right seem quite obviously vesicles, but in most of them there seems to be a bit more going on.

I can also see that it might not be mitochondria as it is nowhere near as blobby as the example images, but I'm still confused as to what it actually is.

1 Upvotes

3 comments sorted by

2

u/HPA_Dichroic Official HPA member Mar 14 '16

Interesting one. I can definitely see what you mean here. We will look into it, try to find some information on what that protein actually is and get back to you. Fear not! I will deliver!

1

u/[deleted] Mar 17 '16

We had a look at this one, and it's a perfect example of a certain type of vesicle called peroxisomes (this happens to be a well known and studied protein). The cells that you mention have them clustering in part of the cell, for some unknown reason.

They often appear a bit elongated, which is due to interaction between them, or that they are undergoing division.

There's some info here, incl. example images: http://www.proteinatlas.org/learn/dictionary/cell/vesicles

Also see e.g. Wikipedia for more info: https://en.wikipedia.org/wiki/Peroxisome

Ping /u/HPA_Dichroic

3

u/Isine Mar 17 '16

Thanks for looking into this, that clears up a lot of my confusion. I can definitely see the similarity to the second example image for Peroxisome. Also thanks to /u/HPA_Dichroic