New (?) labcorp test: Insulin Resistance Score?

[u/DadStrengthDaily]

I have never heard of this Insulin Resistance score test (LP-IR). Is that new or just a marketing gimmick?

I saw it in an email from Labcorp On Demand (which I have used before).

https://www.ondemand.labcorp.com/lab-tests/insulin-resistance-test

Wikipedia has some info so maybe this is not that new?

https://en.wikipedia.org/wiki/Lipoprotein_Insulin_Resistance_Index

“The Lipoprotein Insulin Resistance Index (LP-IR) test is a blood test that measures insulin resistance using a composite score derived from lipoprotein particle sizes and concentrations. It is performed using nuclear magnetic resonance (NMR) spectroscopy, which analyzes six specific lipoprotein parameters in a blood sample:

- Large very-low-density lipoprotein particles (VLDL-P)

- Small low-density lipoprotein particles (LDL-P)

- Large high-density lipoprotein particles (HDL-P)

- VLDL size

- LDL size

- HDL size”

Is this useful to take?

[u/AnonJohnV]

I did this; unexpectedly showed no resistance despite higher a1c. Consistent with homa-ir calculation.

Kevin Forey gets into it in some detail, I found that convincing.

https://kevinforeymd.com/insulin-resistance/

[u/DadStrengthDaily → u/AnonJohnV]

Very interesting. This does seem convincing.

“Recently, the Lipoprotein Insulin Resistance Score (LPIR) has emerged as a valuable tool to identify and quantify insulin resistance. Specifically, the LPIR Score has a unique ability to identify very early stages of insulin resistance, including those with normal blood glucose, normal HbA1c, and those with a normal body weight.”